Protein: EPHA5
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)

Gene: EPHA5
Organism: Homo sapiens
Interactions: 145
UniProt ID: P54756

Gene Ontology (top 5):
GO:0005003 - ephrin receptor activity
GO:0005004 - GPI-linked ephrin receptor activity
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005791 - rough endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

856508

EFNB2
Ephrin-B2

3

20

High-throughput

0.861

High

856595

EFNA5
Ephrin-A5

2

20

High-throughput

0.811

High

665184

EPHA2
Ephrin type-A receptor 2

1

19

High-throughput

0.715

High

665383

EPHA3
Ephrin type-A receptor 3

1

19

High-throughput

0.691

High

872417

EPHB4
Ephrin type-B receptor 4

1

16

High-throughput

0.691

High

872434

PAK2
Serine/threonine-protein kinase PAK 2

1

16

High-throughput

0.691

High

726104

BASI
Basigin

1

15

High-throughput

0.646

High

872457

AN13A
Ankyrin repeat domain-containing protein 13A

1

3

High-throughput

0.646

High

383710

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

120363

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

324761

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

High-throughput

0.618

High

436223

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545285

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

557643

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

655284

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

666048

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.618

High

719689

RADI
Radixin

1

20

High-throughput

0.618

High

776626

STAT3
Signal transducer and activator of transcription 3

1

12

Small-scale

0.618

High

783958

KPCI
Protein kinase C iota type

1

18

High-throughput

0.618

High

872418

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

872419

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

872420

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

872421

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

11

High-throughput

0.618

High

872422

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

872423

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

872424

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

872426

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

19

High-throughput

0.618

High

872428

NOTC2
Neurogenic locus notch homolog protein 2

1

15

High-throughput

0.618

High

872429

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

High-throughput

0.618

High

872431

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

20

High-throughput

0.618

High

872433

DLG1
Disks large homolog 1

1

20

High-throughput

0.618

High

872459

UNC5B
Netrin receptor UNC5B

1

14

High-throughput

0.618

High

872460

MINK1
Misshapen-like kinase 1

1

20

High-throughput

0.618

High

872461

EHBP1
EH domain-binding protein 1

1

18

High-throughput

0.618

High

872464

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.618

High

872473

ERBIN
Erbin

1

13

High-throughput

0.618

High

872492

PKHA1
Pleckstrin homology domain-containing family A member 1

1

20

High-throughput

0.618

High

872493

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.618

High

872494

WDR6
tRNA

1

17

High-throughput

0.618

High

872496

LIN7C
Protein lin-7 homolog C

1

20

High-throughput

0.618

High

872502

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.618

High

872503

DP13A
DCC-interacting protein 13-alpha

1

9

High-throughput

0.618

High

872506

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

15

High-throughput

0.618

High

872510

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

20

High-throughput

0.618

High

237797

TSN3
Tetraspanin-3

3

6

High-throughput

0.609

High

412104

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.590

High

872438

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

17

High-throughput

0.575

High

872454

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

4

High-throughput

0.575

High

872488

DUS21
Dual specificity protein phosphatase 21

1

20

High-throughput

0.555

High

129252

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.553

High

277036

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.553

High

573629

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.553

High

872436

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.553

High

872448

PDZ11
PDZ domain-containing protein 11

1

19

High-throughput

0.553

High

872468

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

20

High-throughput

0.553

High

872470

STAM1
Signal transducing adapter molecule 1

1

20

High-throughput

0.553

High

872489

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

15

High-throughput

0.553

High

872491

PKHA5
Pleckstrin homology domain-containing family A member 5

1

20

High-throughput

0.553

High

872504

KDIS
Kinase D-interacting substrate of 220 kDa

1

12

High-throughput

0.553

High

872458

NRSN1
Neurensin-1

1

1

High-throughput

0.536

High

872463

S22A8
Organic anion transporter 3

1

2

High-throughput

0.536

High

587481

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

16

High-throughput

0.514

High

808060

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

9

High-throughput

0.501

High

872435

ATM
Serine-protein kinase ATM

1

14

Small-scale

0.501

High

815960

ATPO
ATP synthase subunit O, mitochondrial

1

2

High-throughput

0.500

High

872480

NTPCR
Cancer-related nucleoside-triphosphatase

1

9

High-throughput

0.500

High

872432

TRAF2
TNF receptor-associated factor 2

1

9

High-throughput

0.489

High

872447

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.489

High

872487

CST9L
Cystatin-9-like

1

5

High-throughput

0.489

High

872501

FBX2
F-box only protein 2

1

9

High-throughput

0.489

High

209803

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

253546

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

20

High-throughput

0.479

High

280221

CBPD
Carboxypeptidase D

1

7

High-throughput

0.479

High

310571

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

11

High-throughput

0.479

High

320283

SNP29
Synaptosomal-associated protein 29

1

5

High-throughput

0.479

High

542243

PLAK
Junction plakoglobin

1

20

High-throughput

0.479

High

716907

CTNB1
Catenin beta-1

1

20

High-throughput

0.479

High

833552

NUMB
Protein numb homolog

1

18

High-throughput

0.479

High

841961

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

9

High-throughput

0.479

High

872425

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

10

High-throughput

0.479

High

872427

DSC2
Desmocollin-2

1

20

High-throughput

0.479

High

872430

FCHO2
F-BAR domain only protein 2

1

11

High-throughput

0.479

High

872437

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

2

High-throughput

0.479

High

872440

DSG2
Desmoglein-2

1

20

High-throughput

0.479

High

872442

FLOT2
Flotillin-2

1

12

High-throughput

0.479

High

872443

EPN4
Clathrin interactor 1

1

4

High-throughput

0.479

High

872444

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.479

High

872445

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.479

High

872446

AAAT
Neutral amino acid transporter B(0)

1

10

High-throughput

0.479

High

872449

F1711
Protein FAM171A1

1

13

High-throughput

0.479

High

872462

VANG1
Vang-like protein 1

1

5

High-throughput

0.479

High

872469

US6NL
USP6 N-terminal-like protein

1

12

High-throughput

0.479

High

872475

NIBA2
Protein Niban 2

1

6

High-throughput

0.479

High

872477

PKP4
Plakophilin-4

1

20

High-throughput

0.479

High

872479

PKP2
Plakophilin-2

1

20

High-throughput

0.479

High

872484

S38A1
Sodium-coupled neutral amino acid symporter 1

1

2

High-throughput

0.479

High

872485

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

6

High-throughput

0.479

High

872505

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.479

High

872509

NISCH
Nischarin

1

20

High-throughput

0.479

High

438930

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

0

High-throughput

0.458

High

872508

TPPC4
Trafficking protein particle complex subunit 4

1

0

High-throughput

0.458

High

215437

SCO2
Protein SCO2 homolog, mitochondrial

1

2

High-throughput

0.457

High

268431

BAF
Barrier-to-autointegration factor

1

7

High-throughput

0.457

High

778086

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

8

High-throughput

0.457

High

872467

S39A7
Zinc transporter SLC39A7

1

7

High-throughput

0.457

High

872482

PDIP3
Polymerase delta-interacting protein 3

1

3

High-throughput

0.457

High

239877

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

11

High-throughput

0.445

High

872439

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

872472

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

20

High-throughput

0.445

High

872476

SCN2A
Sodium channel protein type 2 subunit alpha

1

10

High-throughput

0.445

High

50335

CA226
Uncharacterized protein C1orf226

1

1

High-throughput

0.437

High

68151

F1712
Protein FAM171A2

1

13

High-throughput

0.437

High

68552

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

3

High-throughput

0.437

High

159937

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

20

High-throughput

0.437

High

240370

SNX2
Sorting nexin-2

1

18

High-throughput

0.437

High

273744

NU155
Nuclear pore complex protein Nup155

1

5

High-throughput

0.437

High

315533

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.437

High

315673

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.437

High

818906

COPD
Coatomer subunit delta

1

7

High-throughput

0.437

High

833057

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

7

High-throughput

0.437

High

848814

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

6

High-throughput

0.437

High

854949

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

11

High-throughput

0.437

High

872441

SEPT6
Septin-6

1

16

High-throughput

0.437

High

872452

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

3

High-throughput

0.437

High

872453

ZFY16
Zinc finger FYVE domain-containing protein 16

1

20

High-throughput

0.437

High

872456

M21D2
Nucleotidyltransferase MB21D2

1

3

High-throughput

0.437

High

872465

SMAP2
Stromal membrane-associated protein 2

1

10

High-throughput

0.437

High

872466

BRK1
Protein BRICK1

1

3

High-throughput

0.437

High

872471

CK5P3
CDK5 regulatory subunit-associated protein 3

1

3

High-throughput

0.437

High

872474

CLCC1
Chloride channel CLIC-like protein 1

1

4

High-throughput

0.437

High

872478

CDCA3
Cell division cycle-associated protein 3

1

9

High-throughput

0.437

High

872481

ESYT1
Extended synaptotagmin-1

1

10

High-throughput

0.437

High

872483

RHG39
Rho GTPase-activating protein 39

1

12

High-throughput

0.437

High

872486

GCP60
Golgi resident protein GCP60

1

10

High-throughput

0.437

High

872490

GORS2
Golgi reassembly-stacking protein 2

1

11

High-throughput

0.437

High

872495

TB22B
TBC1 domain family member 22B

1

7

High-throughput

0.437

High

872497

GGA3
ADP-ribosylation factor-binding protein GGA3

1

20

High-throughput

0.437

High

872498

SEP10
Septin-10

1

14

High-throughput

0.437

High

872499

F135A
Protein FAM135A

1

5

High-throughput

0.437

High

872500

TRM7
tRNA

1

7

High-throughput

0.437

High

872507

SNX6
Sorting nexin-6

1

17

High-throughput

0.437

High

872451

CV042
Uncharacterized protein C22orf42

1

0

High-throughput

0.279

Low

658034

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.249

Low

872450

F91A1
Protein FAM91A1

1

0

High-throughput

0.249

Low

872455

TPPC5
Trafficking protein particle complex subunit 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024