HitPredict

Interactor 1: ACE2 (P21192)
Metallothionein expression activator
Gene: ACE2

Interactor 2: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	18715118, 11027275, 18076379, 26673895
Identification Methods	pull down, two hybrid, affinity chromatography technology, unspecified method
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 770 Sc			1 1084
+	Xl
		1155578 Q6NRD9_XENLA (457-722): 1.64e-44: 173: 24.82		Q6NS03_XENLA (3-1084): 0: 852: 46.77
+	Hs
		162725 KLF5_HUMAN (479-683): 9.84e-44: 166: 22.07		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		162302 KLF8_HUMAN (546-683): 2.08e-42: 159: 22.86		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Sc
		436838 SWI5_YEAST (686-760): 1.51e-12: 73.3: 6.49		MSN5_YEAST (25-223): 1.76e-10: 67.5: 17.01