HitPredict

Interactor 1: PSA7 (P21242)
Probable proteasome subunit alpha type-7 (Macropain subunit C1) (Multicatalytic endopeptidase complex subunit C1) (Proteasome component C1) (Proteinase YSCE subunit 1)
Gene: PRE10

Interactor 2: PSB3 (P25451)
Proteasome subunit beta type-3 (Macropain subunit PUP3) (Multicatalytic endopeptidase complex subunit PUP3) (Proteasome component PUP3)
Gene: PUP3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	16429126, 37968396, 22940862
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0010499 - proteasomal ubiquitin-independent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Sc			1 205
+	Sc
		597203 PSA7_YEAST (1-288): 1.21e-110: 323: 100.00		PSB6_YEAST (3-205): 1.03e-73: 224: 22.52
+	Dm
		771414 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		PSB1_DROME (4-205): 1.85e-76: 231: 30.37
+	Sc
		597211 PSA7_YEAST (1-288): 1.21e-110: 323: 100.00		PSB5_YEAST (4-195): 1.16e-64: 203: 22.80
+	Dm
		1178955 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		Q7K148_DROME (4-205): 1.88e-67: 209: 23.65
+	Hs
		637629 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB8_HUMAN (4-205): 3.16e-69: 214: 23.65
+	Hs
		637634 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB5_HUMAN (8-205): 2.72e-67: 208: 21.11
+	Dm
		1360095 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		Q9W470_DROME (4-194): 2.35e-63: 200: 17.71
+	Dm
		1360096 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		PSB3_DROME (7-205): 6.25e-65: 200: 54.50
+	Dm
		1278639 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		PSA5_DROME (6-205): 7.81e-64: 199: 18.87
+	Hs
		637631 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSA5_HUMAN (6-205): 1.89e-64: 200: 17.14
+	Hs
		637648 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB3_HUMAN (3-205): 5e-64: 198: 53.43
+	Mt
		191406 PSA_METTH (3-253): 3e-97: 287: 34.66		PSB_METTH (1-204): 2.77e-66: 204: 24.39
+	Af
		191426 PSA_ARCFU (1-249): 7.92e-97: 286: 35.74		PSB_ARCFU (6-205): 1.62e-66: 204: 26.37
+	Hs
		594448 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB1_HUMAN (3-205): 9.86e-63: 196: 23.47
+	Dm
		1369061 Q9VK14_DROME (1-283): 1.19e-96: 287: 25.09		PSB3_DROME (7-205): 6.25e-65: 200: 54.50
+	Dm
		1250483 Q9VK14_DROME (1-283): 1.19e-96: 287: 25.09		Q8T8V8_DROME (7-196): 2.31e-61: 195: 19.90
+	Ph
		223381 PSA_PYRHO (6-241): 1.86e-98: 291: 37.29		PSB1_PYRHO (5-202): 1.33e-59: 186: 21.50
+	Dm
		47616 PSA3_DROME (1-260): 9.48e-102: 299: 43.30		A0AQH0_DROME (1-200): 1.38e-30: 113: 20.40
+	Hs
		637630 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB9_HUMAN (5-200): 6.23e-30: 111: 20.81
+	Hs
		637633 PSA2_HUMAN (6-235): 6.77e-100: 294: 34.35		PSB6_HUMAN (5-200): 1.04e-28: 108: 18.78