HitPredict

Interactor 1: VATB2 (P21281)
V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)
Gene: ATP6V1B2

Interactor 2: VATE1 (P36543)
V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)
Gene: ATP6V1E1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 35271311, 33961781, 35235311
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_ab~vATP-synt_E, ATP-synt_ab_N~vATP-synt_E
Common GO terms GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0005902 - microvillus
GO:0016241 - regulation of macroautophagy
and 6 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 511
Hs

1 226
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024