Protein: SPTB2
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain)

Gene: SPTB2, Sptbn1
Organism: Mus musculus
Interactions: 54
UniProt ID: Q62261

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005516 - calmodulin binding
GO:0005543 - phospholipid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

104544

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

10

High-throughput

0.667

High

1193757

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

20

High-throughput

0.650

High

1223545

DLG4
Disks large homolog 4

3

17

High-throughput

0.650

High

60097

KALRN
Kalirin

1

19

High-throughput

0.618

High

109265

ANK3
Ankyrin-3

1

19

High-throughput

0.618

High

236902

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.618

High

1223935

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

19

High-throughput

0.618

High

1223956

DLGP1
Disks large-associated protein 1

2

3

High-throughput

0.611

High

1223938

NEB2
Neurabin-2

2

20

High-throughput

0.584

High

312828

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.536

High

1013598

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.536

High

1190139

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

7

High-throughput

0.536

High

1196079

HERC2
E3 ubiquitin-protein ligase HERC2

1

9

High-throughput

0.536

High

1210163

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

9

High-throughput

0.536

High

1223937

HDAC4
Histone deacetylase 4

1

18

High-throughput

0.536

High

1223940

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.536

High

1223941

EPOP
Elongin BC and Polycomb repressive complex 2-associated protein

1

2

Small-scale

0.536

High

1223942

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

9

High-throughput

0.536

High

1223944

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

20

High-throughput

0.536

High

1223945

MYOME
Myomegalin

1

20

High-throughput

0.536

High

1223947

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

7

High-throughput

0.536

High

1223950

PEX5R
PEX5-related protein

1

3

High-throughput

0.536

High

1223959

HOME1
Homer protein homolog 1

1

20

High-throughput

0.536

High

236590

ITB3
Integrin beta-3

1

20

High-throughput

0.501

High

549386

ITB2
Integrin beta-2

1

20

High-throughput

0.501

High

704283

NCKP1
Nck-associated protein 1

1

3

High-throughput

0.489

High

1223939

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

9

High-throughput

0.489

High

771479

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

16

High-throughput

0.484

High

644340

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

9

High-throughput

0.479

High

723388

SSR3
Somatostatin receptor type 3

1

5

High-throughput

0.479

High

838290

STAT3
Signal transducer and activator of transcription 3

1

6

Small-scale

0.479

High

921259

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

Small-scale

0.479

High

947698

NPHP4
Nephrocystin-4

1

3

High-throughput

0.479

High

989978

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1021572

RGS14
Regulator of G-protein signaling 14

1

6

High-throughput

0.479

High

1191071

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

11

High-throughput

0.479

High

1223943

FACD2
Fanconi anemia group D2 protein homolog

1

9

High-throughput

0.479

High

1223951

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

1223953

OTU7A
OTU domain-containing protein 7A

1

11

High-throughput

0.479

High

1223954

EED
Polycomb protein EED

1

14

High-throughput

0.479

High

1223955

HSPB2
Heat shock protein beta-2

1

12

High-throughput

0.479

High

1223958

SPAST
Spastin

1

10

High-throughput

0.479

High

1223960

KCNQ2
Potassium voltage-gated channel subfamily KQT member 2

1

18

High-throughput

0.479

High

1223952

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

2

High-throughput

0.457

High

777909

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.445

High

905865

CAV3
Caveolin-3

1

15

High-throughput

0.445

High

1223949

RD3
Protein RD3

1

2

Small-scale

0.445

High

1223957

SRCN1
SRC kinase signaling inhibitor 1

1

11

High-throughput

0.445

High

97607

E9PV60
WD repeat and FYVE domain containing 4

1

9

High-throughput

0.437

High

108710

G3X9H5
Huntingtin

1

7

High-throughput

0.437

High

1223936

TEDC2
Tubulin epsilon and delta complex protein 2

1

3

High-throughput

0.437

High

1223946

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

17

High-throughput

0.437

High

1223948

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.437

High


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Last updated: 11Aug2025