HitPredict

Interactor 1: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.802

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 576 Sc			1 375
+	Hs
		903280 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		891660 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		903110 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		932452 FZR1_HUMAN (337-559): 3.4e-22: 102: 16.96		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		792947 LIS1_HUMAN (468-561): 5.16e-11: 66.7: 10.42		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		792968 LIS1_HUMAN (468-561): 5.16e-11: 66.7: 10.42		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		932318 SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34		ACTC_HUMAN (2-375): 0: 591: 87.17