HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: ITB7 (P26010)
Integrin beta-7 (Gut homing receptor beta subunit)
Gene: ITGB7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.908

The method score is based on:

Property Details
Experiments 11781567, 21926999, 15225631, 17690686
Identification Methods pull down, anti tag coimmunoprecipitation, saturation binding, filter binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filamin~Integrin_b_cyt
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0016020 - membrane
GO:0043113 - receptor clustering
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2647
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024