HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	35973513, 37120454, 17461779
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0043066 - negative regulation of apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 1708
+	Hs
		261283 FLNB_HUMAN (28-2647): 0: 2710: 69.63		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1052891 FLNC_HUMAN (32-2647): 0: 1432: 35.96		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		963353 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		521564 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		211601 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		RICTR_HUMAN (1-1708): 0: 2775: 100.00