HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 548
+	Hs
		261322 FLNB_HUMAN (28-2647): 0: 2710: 69.63		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		598309 FLNA_HUMAN (1-2647): 0: 2776: 100.00		TRIM6_HUMAN (13-420): 1.73e-74: 246: 13.13
+	Hs
		62677 FLNA_HUMAN (1-2647): 0: 2776: 100.00		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		598377 FLNA_HUMAN (1-2647): 0: 2776: 100.00		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		598187 FLNA_HUMAN (1-2647): 0: 2776: 100.00		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		261288 FLNB_HUMAN (28-2647): 0: 2710: 69.63		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1052933 FLNC_HUMAN (32-2647): 0: 1432: 35.96		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		1052919 FLNC_HUMAN (32-2647): 0: 1432: 35.96		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1052932 FLNC_HUMAN (32-2647): 0: 1432: 35.96		TRI54_HUMAN (1-353): 3.29e-78: 252: 62.54
+	Hs
		211440 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		521464 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		521640 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		211495 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Mm
		1186640 ACTN1_MOUSE (20-459): 2.62e-118: 400: 24.12		TRI59_MOUSE (17-301): 3.82e-65: 219: 23.08
+	Hs
		62673 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		TRI64_HUMAN (13-398): 3.94e-71: 236: 15.13
+	Hs
		211693 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		TRI33_HUMAN (25-531): 1.06e-65: 233: 10.86
+	Hs
		963355 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		521567 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		211603 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39