HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: BACD3 (Q9H3F6)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (hBACURD3) (BTB/POZ domain-containing protein KCTD10) (Potassium channel tetramerization domain-containing protein 10)
Gene: KCTD10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 313
+	Hs
		598252 FLNA_HUMAN (1-2647): 0: 2776: 100.00		BACD1_HUMAN (17-313): 2.33e-105: 312: 68.44
+	Hs
		598355 FLNA_HUMAN (1-2647): 0: 2776: 100.00		KCND2_HUMAN (4-233): 2.73e-62: 210: 15.90
+	Hs
		598229 FLNA_HUMAN (1-2647): 0: 2776: 100.00		KCD17_HUMAN (32-156): 3.05e-39: 142: 32.82
+	Hs
		598194 FLNA_HUMAN (1-2647): 0: 2776: 100.00		KCTD9_HUMAN (17-156): 1.3e-37: 139: 28.47
+	Hs
		261290 FLNB_HUMAN (28-2647): 0: 2710: 69.63		KCTD9_HUMAN (17-156): 1.3e-37: 139: 28.47
+	Hs
		1045918 FLNC_HUMAN (32-2647): 0: 1432: 35.96		BACD2_HUMAN (4-313): 9.13e-120: 348: 70.06
+	Hs
		1052911 FLNC_HUMAN (32-2647): 0: 1432: 35.96		BACD1_HUMAN (17-313): 2.33e-105: 312: 68.44
+	Hs
		1052954 FLNC_HUMAN (32-2647): 0: 1432: 35.96		KCND2_HUMAN (4-233): 2.73e-62: 210: 15.90
+	Hs
		608218 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		KCNA4_HUMAN (20-229): 1.46e-45: 165: 16.97
+	Hs
		963357 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		KCTD9_HUMAN (17-156): 1.3e-37: 139: 28.47
+	Ce
		1095233 Q23158_CAEEL (23-268): 6.21e-105: 362: 32.93		Q9TZA6_CAEEL (29-216): 1.86e-54: 178: 31.47
+	Hs
		521580 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		KCTD6_HUMAN (32-164): 2.89e-36: 132: 30.15
+	Hs
		70404 B2R8Y4_HUMAN (30-460): 2.45e-118: 401: 25.28		KCTD6_HUMAN (32-164): 2.89e-36: 132: 30.15
+	Hs
		993276 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		KCTD6_HUMAN (32-164): 2.89e-36: 132: 30.15
+	Ce
		954549 Q23158_CAEEL (23-268): 6.21e-105: 362: 32.93		P91563_CAEEL (31-204): 8.25e-51: 169: 33.52
+	Hs
		211604 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		KCTD9_HUMAN (17-156): 1.3e-37: 139: 28.47
+	Dm
		1364784 FLNA_DROME (2539-2646): 9.6e-12: 73.5: 28.57		Q9W579_DROME (31-156): 6.73e-37: 132: 29.55