Interactor 1: ISY1 (P21374)
Pre-mRNA-splicing factor ISY1 (Interactor of SYF1) (PRP19-associated complex protein 30)
Gene: ISY1

Interactor 2: CLF1 (Q12309)
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)
Gene: CLF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 11842115, 11102353, 11805826, 37968396, 16429126, 12509417
Identification Methods coimmunoprecipitation, two hybrid, tandem affinity purification, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000974 - Prp19 complex
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 235
Sc

1 687
+ Hs
+ Dm
+ Sc
+ Dm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024