Protein: SNP25
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)

Gene: SNP25, SNAP25
Organism: Homo sapiens
Interactions: 80
UniProt ID: P60880

Gene Ontology (top 5):
GO:0001504 - neurotransmitter uptake
GO:0001917 - photoreceptor inner segment
GO:0005249 - voltage-gated potassium channel activity
GO:0005484 - SNAP receptor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

954395

STX1A
Syntaxin-1A

14

20

Small-scale

0.760

High

954385

VAMP2
Vesicle-associated membrane protein 2

6

20

Small-scale

0.721

High

286640

STX11
Syntaxin-11

5

20

High-throughput

0.718

High

165139

CPLX1
Complexin-1

4

3

Small-scale

0.683

High

639115

SYT1
Synaptotagmin-1

4

8

Small-scale

0.680

High

954387

STX4
Syntaxin-4

3

20

Small-scale

0.670

High

954389

STX3
Syntaxin-3

3

20

Small-scale

0.646

High

954396

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.638

High

954417

KTU
Protein kintoun

3

0

High-throughput

0.638

High

333315

SNAPN
SNARE-associated protein Snapin

2

2

Small-scale

0.629

High

954393

ITSN1
Intersectin-1

2

6

Small-scale

0.629

High

954410

TRIM9
E3 ubiquitin-protein ligase TRIM9

2

1

Small-scale

0.624

High

954401

STX12
Syntaxin-12

3

20

Small-scale

0.624

High

954403

STX19
Syntaxin-19

2

20

High-throughput

0.606

High

843438

HD
Huntingtin

2

3

High-throughput

0.588

High

954406

UQCC2
Ubiquinol-cytochrome c reductase complex assembly factor 2

2

0

High-throughput

0.580

High

363069

EGFR
Epidermal growth factor receptor

2

7

Small-scale

0.565

High

934360

TERA
Transitional endoplasmic reticulum ATPase

2

1

Small-scale

0.552

High

954400

PRRT2
Proline-rich transmembrane protein 2

1

1

High-throughput

0.541

High

954421

WASC3
WASH complex subunit 3

1

0

High-throughput

0.536

High

302048

SEGN
Secretagogin

1

1

High-throughput

0.536

High

328655

VAMP5
Vesicle-associated membrane protein 5

1

20

High-throughput

0.536

High

529465

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

749884

KINH
Kinesin-1 heavy chain

1

3

Small-scale

0.527

High

954411

SRCN1
SRC kinase signaling inhibitor 1

1

1

Small-scale

0.527

High

954413

OSBL2
Oxysterol-binding protein-related protein 2

1

7

Small-scale

0.527

High

281302

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.513

High

906859

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

178752

SCAM1
Secretory carrier-associated membrane protein 1

1

3

Small-scale

0.501

High

331851

GOSR1
Golgi SNAP receptor complex member 1

1

3

Small-scale

0.501

High

421831

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

746187

STX2
Syntaxin-2

1

20

Small-scale

0.501

High

907992

VAMP7
Vesicle-associated membrane protein 7

1

20

Small-scale

0.501

High

932987

SNAA
Alpha-soluble NSF attachment protein

1

16

Small-scale

0.501

High

954388

STX5
Syntaxin-5

1

20

Small-scale

0.501

High

954392

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

1

Small-scale

0.501

High

954405

SYT3
Synaptotagmin-3

1

8

Small-scale

0.501

High

643353

OSBP1
Oxysterol-binding protein 1

1

7

Small-scale

0.481

High

954407

OSB11
Oxysterol-binding protein-related protein 11

1

8

Small-scale

0.481

High

954408

OSB10
Oxysterol-binding protein-related protein 10

1

8

Small-scale

0.481

High

954409

OSBL8
Oxysterol-binding protein-related protein 8

1

8

Small-scale

0.481

High

954412

OSBL5
Oxysterol-binding protein-related protein 5

1

8

Small-scale

0.481

High

954422

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

169491

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

4

Small-scale

0.479

High

375338

RASK
GTPase KRas

1

11

High-throughput

0.479

High

555985

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

954420

RP3A
Rabphilin-3A

1

8

Small-scale

0.479

High

189488

STX7
Syntaxin-7

1

20

Small-scale

0.445

High

343343

SNP29
Synaptosomal-associated protein 29

1

8

Small-scale

0.445

High

408774

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

Small-scale

0.445

High

536861

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.445

High

605513

SYN1
Synapsin-1

1

1

Small-scale

0.445

High

630414

RAB3A
Ras-related protein Rab-3A

1

5

Small-scale

0.445

High

662335

VAMP1
Vesicle-associated membrane protein 1

1

20

Small-scale

0.445

High

791234

SYUA
Alpha-synuclein

1

1

Small-scale

0.445

High

857074

NSF
Vesicle-fusing ATPase

1

8

Small-scale

0.445

High

954380

STX1B
Syntaxin-1B

1

20

Small-scale

0.445

High

954382

VA0D1
V-type proton ATPase subunit d 1

1

1

Small-scale

0.445

High

954383

STXB1
Syntaxin-binding protein 1

1

14

Small-scale

0.445

High

954384

RAB1A
Ras-related protein Rab-1A

1

2

Small-scale

0.445

High

954386

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.445

High

954397

Q59EP4
Mel transforming oncogene variant

1

6

Small-scale

0.445

High

954398

CPLX2
Complexin-2

1

3

Small-scale

0.445

High

954399

ZNT10
Calcium/manganese antiporter SLC30A10

1

4

High-throughput

0.445

High

954402

ZDH17
Palmitoyltransferase ZDHHC17

1

2

Small-scale

0.445

High

954404

SEPT5
Septin-5

1

3

Small-scale

0.445

High

954416

RAB6B
Ras-related protein Rab-6B

1

9

Small-scale

0.445

High

420780

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

Small-scale

0.426

High

443743

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

0

Small-scale

0.426

High

784569

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

Small-scale

0.426

High

861095

MAP1B
Microtubule-associated protein 1B

1

0

Small-scale

0.426

High

954381

SMS
Somatostatin

1

0

Small-scale

0.426

High

954391

FHL1
Four and a half LIM domains protein 1

1

0

Small-scale

0.426

High

954394

VAS1
V-type proton ATPase subunit S1

1

0

Small-scale

0.426

High

954414

TTYH1
Protein tweety homolog 1

1

0

Small-scale

0.426

High

954419

Q9UL88
Myosin-reactive immunoglobulin heavy chain variable region

1

0

Small-scale

0.426

High

954418

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

954390

ZN177
Zinc finger protein 177

2

0

High-throughput

0.316

High

105671

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

954415

Q9NP29
Microfibrillar protein 2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025