HitPredict

Interactor 1: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Interactor 2: CD47 (Q08722)
Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47)
Gene: CD47

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 323
+	Hs
		996250 LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51		CD47_HUMAN (1-323): 0: 526: 100.00
+	Hs
		996258 LPAR2_HUMAN (23-365): 5.55e-76: 240: 34.88		CD47_HUMAN (1-323): 0: 526: 100.00
+	Hs
		686649 CCR1_HUMAN (27-360): 7.95e-64: 209: 14.29		CD47_HUMAN (1-323): 0: 526: 100.00
+	Mm
		677293 SSR3_MOUSE (1-343): 1.19e-64: 213: 18.08		CD47_MOUSE (1-303): 1.9e-178: 497: 70.30