Interactor 1: RIR1 (P21524)
Ribonucleoside-diphosphate reductase large chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R1 subunit 1) (Ribonucleotide reductase large subunit 1)
Gene: RNR1

Interactor 2: RIR1 (P21524)
Ribonucleoside-diphosphate reductase large chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R1 subunit 1) (Ribonucleotide reductase large subunit 1)
Gene: RNR1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.942

The method score is based on:

Property Details
Experiments 9774971, 27155231, 16537479, 16537480, 17277086, 21336276
Identification Methods two hybrid, molecular sieving, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-cone~ATP-cone, ATP-cone~Ribonuc_red_lgC, ATP-cone~Ribonuc_red_lgN, Ribonuc_red_lgC~Ribonuc_red_lgC, Ribonuc_red_lgC~Ribonuc_red_lgN
Common GO terms GO:0000166 - nucleotide binding
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 888
Sc

1 888
+ Sc
+ Hs
+ Vv
+ Ec
+ Ha
+ Hh
+ Hh
+ Ha
+ Mb

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024