Protein: IL7RA
Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)

Gene: IL7RA, IL7R
Organism: Homo sapiens
Interactions: 151
UniProt ID: P16871

Gene Ontology (top 5):
GO:0000018 - regulation of DNA recombination
GO:0000902 - cell morphogenesis
GO:0001782 - B cell homeostasis
GO:0001913 - T cell mediated cytotoxicity
GO:0001915 - negative regulation of T cell mediated cytotoxicity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561004

IL7
Interleukin-7

4

0

Small-scale

0.860

High

599165

IL2RG
Cytokine receptor common subunit gamma

3

2

Small-scale

0.827

High

599178

JAK3
Tyrosine-protein kinase JAK3

2

4

Small-scale

0.754

High

599227

CISH
Cytokine-inducible SH2-containing protein

2

4

Small-scale

0.754

High

599205

EPHA7
Ephrin type-A receptor 7

1

1

High-throughput

0.691

High

532041

KIT
Mast/stem cell growth factor receptor Kit

1

0

Small-scale

0.687

High

599173

KPCI
Protein kinase C iota type

1

0

High-throughput

0.656

High

599208

LAMA3
Laminin subunit alpha-3

1

0

High-throughput

0.656

High

440345

FYN
Tyrosine-protein kinase Fyn

1

0

Small-scale

0.631

High

155074

SOCS2
Suppressor of cytokine signaling 2

1

4

Small-scale

0.618

High

193201

SOCS1
Suppressor of cytokine signaling 1

1

5

Small-scale

0.618

High

407971

TBB4A
Tubulin beta-4A chain

1

4

High-throughput

0.618

High

457214

TBB5
Tubulin beta chain

1

4

High-throughput

0.618

High

599146

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.618

High

599148

JAK1
Tyrosine-protein kinase JAK1

1

3

High-throughput

0.618

High

599152

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.618

High

599157

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.618

High

599170

STAT3
Signal transducer and activator of transcription 3

1

2

High-throughput

0.618

High

599174

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

High-throughput

0.618

High

599175

STA5A
Signal transducer and activator of transcription 5A

1

2

High-throughput

0.618

High

599184

MTPN
Myotrophin

1

1

High-throughput

0.618

High

599187

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.618

High

599192

TBA4A
Tubulin alpha-4A chain

1

5

High-throughput

0.618

High

599193

TBB4B
Tubulin beta-4B chain

1

4

High-throughput

0.618

High

599203

FAK2
Protein-tyrosine kinase 2-beta

1

2

Small-scale

0.618

High

599211

TBA1A
Tubulin alpha-1A chain

1

6

High-throughput

0.618

High

387944

FIBG
Fibrinogen gamma chain

1

0

High-throughput

0.586

High

568116

PLSL
Plastin-2

1

0

High-throughput

0.586

High

599147

CBL
E3 ubiquitin-protein ligase CBL

1

0

Small-scale

0.586

High

599155

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.586

High

599169

TAGL2
Transgelin-2

1

0

High-throughput

0.586

High

599206

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.586

High

331463

APOL3
Apolipoprotein L3

2

0

High-throughput

0.580

High

549426

CD20
B-lymphocyte antigen CD20

2

0

High-throughput

0.580

High

599164

SDC4
Syndecan-4

2

0

High-throughput

0.580

High

599199

MALL
MAL-like protein

2

0

High-throughput

0.580

High

599210

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.580

High

599226

PRD10
PR domain zinc finger protein 10

1

0

High-throughput

0.578

High

599212

CD302
CD302 antigen

1

0

High-throughput

0.556

High

599191

TBA1B
Tubulin alpha-1B chain

1

6

High-throughput

0.553

High

599201

TBB2A
Tubulin beta-2A chain

1

4

High-throughput

0.553

High

599221

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.553

High

599223

TBB6
Tubulin beta-6 chain

1

4

High-throughput

0.553

High

599225

TBB1
Tubulin beta-1 chain

1

6

High-throughput

0.553

High

599228

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.553

High

599171

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

2

1

High-throughput

0.549

High

599214

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.546

High

599216

VANG1
Vang-like protein 1

1

1

High-throughput

0.536

High

599217

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

1

High-throughput

0.536

High

599230

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

1

High-throughput

0.536

High

599232

VANG2
Vang-like protein 2

1

1

High-throughput

0.536

High

599236

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

1

High-throughput

0.536

High

599195

TF65
Transcription factor p65

1

1

Small-scale

0.534

High

123221

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.517

High

599218

FAM3C
Protein FAM3C

1

1

High-throughput

0.515

High

252819

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.513

High

478441

FGF2
Fibroblast growth factor 2

1

0

High-throughput

0.513

High

599183

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.513

High

599194

AMPD2
AMP deaminase 2

1

0

High-throughput

0.513

High

599197

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.513

High

599200

SQSTM
Sequestosome-1

1

0

High-throughput

0.513

High

599213

TM192
Transmembrane protein 192

1

0

High-throughput

0.513

High

599215

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.513

High

599235

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.513

High

446614

NPM
Nucleophosmin

1

0

High-throughput

0.493

High

328626

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.493

High

599153

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.493

High

158910

CCS
Copper chaperone for superoxide dismutase

1

1

High-throughput

0.479

High

361102

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

412926

CPNS1
Calpain small subunit 1

1

1

High-throughput

0.479

High

437564

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

2

High-throughput

0.479

High

445721

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

447663

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

452157

PDIA1
Protein disulfide-isomerase

1

2

High-throughput

0.479

High

472233

MYL3
Myosin light chain 3

1

2

High-throughput

0.479

High

479108

ENOG
Gamma-enolase

1

1

High-throughput

0.479

High

480687

LEG1
Galectin-1

1

1

High-throughput

0.479

High

528178

THIO
Thioredoxin

1

1

High-throughput

0.479

High

534600

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

536442

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

582654

EZRI
Ezrin

1

1

High-throughput

0.479

High

599144

HSP76
Heat shock 70 kDa protein 6

1

2

High-throughput

0.479

High

599149

COF1
Cofilin-1

1

1

High-throughput

0.479

High

599150

MOES
Moesin

1

1

High-throughput

0.479

High

599158

ERP29
Endoplasmic reticulum resident protein 29

1

3

High-throughput

0.479

High

599159

PRDX6
Peroxiredoxin-6

1

2

High-throughput

0.479

High

599160

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

2

High-throughput

0.479

High

599163

SORCN
Sorcin

1

1

High-throughput

0.479

High

599166

1433B
14-3-3 protein beta/alpha

1

1

High-throughput

0.479

High

599167

PRDX2
Peroxiredoxin-2

1

2

High-throughput

0.479

High

599168

HS71L
Heat shock 70 kDa protein 1-like

1

2

High-throughput

0.479

High

599185

MYL6
Myosin light polypeptide 6

1

2

High-throughput

0.479

High

599186

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.479

High

599188

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

599189

ACTG
Actin, cytoplasmic 2

1

1

High-throughput

0.479

High

599190

TPM4
Tropomyosin alpha-4 chain

1

1

High-throughput

0.479

High

599196

PSME1
Proteasome activator complex subunit 1

1

1

High-throughput

0.479

High

599198

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.479

High

599202

COTL1
Coactosin-like protein

1

1

High-throughput

0.479

High

599204

PDIA6
Protein disulfide-isomerase A6

1

2

High-throughput

0.479

High

599229

DBNL
Drebrin-like protein

1

1

High-throughput

0.479

High

599231

PSME2
Proteasome activator complex subunit 2

1

1

High-throughput

0.479

High

238378

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.460

High

131122

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.458

High

192687

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.458

High

227359

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

277885

SH3L1
Adapter SH3BGRL

1

0

High-throughput

0.458

High

361688

F13A
Coagulation factor XIII A chain

1

0

High-throughput

0.458

High

387223

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.458

High

389788

TTHY
Transthyretin

1

0

High-throughput

0.458

High

389951

ALBU
Albumin

1

0

High-throughput

0.458

High

390317

CXCL7
Platelet basic protein

1

0

High-throughput

0.458

High

390857

TRFE
Serotransferrin

1

0

High-throughput

0.458

High

405177

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

408658

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

415330

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.458

High

442225

GELS
Gelsolin

1

0

High-throughput

0.458

High

443648

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

0

High-throughput

0.458

High

450924

LDHB
L-lactate dehydrogenase B chain

1

0

High-throughput

0.458

High

459443

PROF1
Profilin-1

1

0

High-throughput

0.458

High

459863

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.458

High

470419

ITA2B
Integrin alpha-IIb

1

0

High-throughput

0.458

High

471456

PLEK
Pleckstrin

1

0

High-throughput

0.458

High

476551

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

479760

GSTP1
Glutathione S-transferase P

1

0

High-throughput

0.458

High

532340

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

599145

VINC
Vinculin

1

0

High-throughput

0.458

High

599151

S10A4
Protein S100-A4

1

0

High-throughput

0.458

High

599154

CALR
Calreticulin

1

0

High-throughput

0.458

High

599156

PSA5
Proteasome subunit alpha type-5

1

0

High-throughput

0.458

High

599161

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

599172

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

599176

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.458

High

599177

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.458

High

599179

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

599180

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.458

High

599181

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.458

High

599182

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

599207

ZYX
Zyxin

1

0

High-throughput

0.458

High

599220

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

599233

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.458

High

336258

BRI3
Membrane protein BRI3

1

0

Small-scale

0.438

High

599162

PDIA3
Protein disulfide-isomerase A3

1

2

High-throughput

0.437

High

599209

LEGL
Galectin-related protein

1

1

High-throughput

0.437

High

599234

COF2
Cofilin-2

1

1

High-throughput

0.437

High

49625

T120B
Transmembrane protein 120B

2

0

High-throughput

0.316

High

71285

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

502225

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

599219

MITOK
Mitochondrial potassium channel

1

0

High-throughput

0.279

Low

599222

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

599224

TMM60
Transmembrane protein 60

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025