HitPredict

Interactor 1: FOSLA (P21525)
Transcription factor kayak, isoforms A/B/F (AP-1) (Fos-related antigen) (Dfos) (dFra)
Gene: kay

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16391236
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 755 Dm			1 521
+	Hs
		345504 FOS_HUMAN (322-624): 2.08e-41: 157: 23.66		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Mm
		450547 JUNB_MOUSE (145-488): 3.16e-41: 156: 15.17		HDAC2_MOUSE (2-488): 0: 655: 76.18
+	Mm
		140216 JUNB_MOUSE (145-488): 3.16e-41: 156: 15.17		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		402302 JUN_HUMAN (239-495): 7.01e-28: 117: 15.11		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Hs
		556932 CREB1_HUMAN (145-473): 3.86e-28: 117: 15.96		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Mm
		140232 CREM_MOUSE (123-469): 4.73e-33: 132: 11.36		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		401956 JUN_HUMAN (239-495): 7.01e-28: 117: 15.11		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		556861 CREB1_HUMAN (145-473): 3.86e-28: 117: 15.96		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		936396 ATF3_MOUSE (412-499): 1.43e-22: 97.6: 37.50		HDAC2_MOUSE (2-488): 0: 655: 76.18
+	Hs
		548245 FOSL1_HUMAN (343-557): 5.01e-24: 104: 24.42		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		177140 CREB3_HUMAN (302-619): 5.33e-44: 164: 16.43		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Ce
		105173 FOS1_CAEEL (287-615): 9.93e-31: 128: 18.85		HDA1_CAEEL (1-456): 0: 593: 64.05
+	Hs
		177376 BACH2_HUMAN (221-590): 1.3e-35: 146: 15.04		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Sp
		223487 ATF1_SCHPO (158-498): 5.24e-40: 157: 20.82		CLR6_SCHPO (2-403): 0: 553: 60.25
+	Mm
		404159 JUN_MOUSE (239-495): 6.1e-30: 123: 15.61		Q9JM08_MOUSE (6-427): 0: 567: 56.13
+	Hs
		177168 JUN_HUMAN (239-495): 7.01e-28: 117: 15.11		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Mm
		1141349 ATF3_MOUSE (412-499): 1.43e-22: 97.6: 37.50		Q9JM08_MOUSE (6-427): 0: 567: 56.13
+	Hs
		547761 ATF2_HUMAN (179-568): 1.14e-50: 187: 19.25		HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86
+	Mm
		964095 CREB1_MOUSE (164-473): 4.09e-28: 117: 16.61		HDAC4_MOUSE (5-405): 1.49e-134: 418: 23.83
+	Hs
		556960 CREB1_HUMAN (145-473): 3.86e-28: 117: 15.96		HDAC8_HUMAN (30-369): 4.56e-139: 407: 42.82