HitPredict

Interactor 1: A4FUW1 (A4FUW1)
4932417H02Rik protein
Gene: Rptor

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0009267 - cellular response to starvation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1333 Mm			1 1161
+	Mm
		1225301 RPTOR_MOUSE (1-1333): 0: 1474: 99.93		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		724912 RPTOR_HUMAN (1-1333): 0: 1450: 96.62		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		1267512 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		148610 WDR5_HUMAN (1097-1332): 5.55e-64: 223: 16.39		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		1022819 STRN3_HUMAN (594-1326): 7.05e-80: 282: 10.71		SLMAP_HUMAN (681-959): 6.71e-09: 62.5: 20.13
+	Hs
		551655 WDR5_HUMAN (1097-1332): 5.55e-64: 223: 16.39		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		903399 WDR5_HUMAN (1097-1332): 5.55e-64: 223: 16.39		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		551659 GBB2_HUMAN (1036-1333): 1.48e-56: 201: 12.91		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		724753 GBB2_HUMAN (1036-1333): 1.48e-56: 201: 12.91		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		551632 LIS1_HUMAN (1099-1332): 5.88e-55: 199: 15.29		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		551766 WDR5B_HUMAN (1198-1332): 1.55e-29: 122: 12.41		DESP_HUMAN (548-1138): 1.55e-25: 117: 11.54
+	Hs
		724952 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		148462 COPB2_HUMAN (1195-1331): 3.7e-15: 82.9: 17.99		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		1268063 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		1281519 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		MRCKB_HUMAN (421-862): 5.66e-16: 85.6: 11.45
+	Hs
		1067456 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		EEA1_HUMAN (408-851): 3.09e-13: 76.8: 8.35
+	Dm
		1001661 Q0KHS0_DROME (1065-1318): 8.64e-17: 88.3: 20.54		Q7JQV2_DROME (691-960): 1.41e-17: 90.7: 16.72
+	Hs
		725215 FBXW7_HUMAN (1192-1332): 4.22e-24: 111: 16.67		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Hs
		728492 POC1A_HUMAN (838-1112): 4.12e-16: 84.1: 9.61		MYH11_HUMAN (796-1161): 5.47e-11: 69.5: 12.30
+	Hs
		725440 COPB2_HUMAN (1195-1331): 3.7e-15: 82.9: 17.99		SLMAP_HUMAN (681-959): 6.71e-09: 62.5: 20.13