HitPredict

Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: TNIP3 (Q96KP6)
TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein)
Gene: TNIP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.668

The method score is based on:

Property Details
Experiments 32599618, 25416956, 17088249
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0043124 - negative regulation of canonical NF-kappaB signal transduction
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 790
Hs

1 325
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Last updated: 15 Jul 2024