HitPredict - High confidence protein-protein interactions

Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: SHRPN (Q9H0F6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (hSIPL1)
Gene: SHARPIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Method score

Annotation score

Interaction score

0.67

0.60

0.635

Property	Details
Experiments	30561431, 23032186
Identification Methods	affinity chromatography technology, virotrap, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property

Details

Experiments

30561431, 23032186

Identification Methods

affinity chromatography technology, virotrap, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation

Interaction Type

physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway GO:0043130 - ubiquitin binding GO:0050728 - negative regulation of inflammatory response
Homologous interactions	2

Property

Details

Interacting Pfam domains

Common GO terms

GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway
GO:0043130 - ubiquitin binding
GO:0050728 - negative regulation of inflammatory response

Homologous interactions