HitPredict

Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	23018911, 19131965, 22507528, 15231748
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 790 Hs			1 154
+	Hs
		599738 TNAP3_HUMAN (1-790): 0: 1520: 100.00		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Mm
		1141364 TNAP3_MOUSE (1-790): 0: 1470: 88.10		RNF11_MOUSE (1-154): 1.27e-42: 140: 99.35
+	Hs
		1151640 OTU7B_HUMAN (39-299): 1.32e-98: 326: 37.37		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1346937 ZRAN1_HUMAN (47-308): 4.61e-97: 318: 33.79		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29