HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34056863
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1893 Hs			1 616
+	Hs
		651051 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651796 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		652613 TRI33_HUMAN (1113-1671): 3.28e-64: 242: 12.83		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651853 KAT2B_HUMAN (1392-1504): 3.93e-32: 138: 29.20		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		652353 BAZ1A_HUMAN (1078-1649): 3.96e-29: 130: 13.99		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Hs
		651852 KAT2A_HUMAN (1392-1504): 1.96e-29: 129: 29.20		RFA1_HUMAN (1-616): 0: 781: 100.00
+	Sc
		607326 RSC4_YEAST (1350-1638): 7.86e-44: 172: 20.78		RFA1_YEAST (4-615): 0: 596: 31.69
+	Sc
		607253 BDF1_YEAST (1164-1506): 3.83e-28: 124: 10.90		RFA1_YEAST (4-615): 0: 596: 31.69
+	Sc
		603276 SNF2_YEAST (1117-1636): 8.21e-21: 102: 12.06		RFA1_YEAST (4-615): 0: 596: 31.69