Interactor 1: EME2 (A4GXA9)
Probable crossover junction endonuclease EME2 (EC 3.1.22.-)
Gene: EME2

Interactor 2: MUS81 (Q96NY9)
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
Gene: MUS81

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.681

The method score is based on:

Property Details
Experiments 17289582
Identification Methods pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC4~ERCC4
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0006302 - double-strand break repair
GO:0008821 - crossover junction DNA endonuclease activity
GO:0031297 - replication fork processing
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 379
Hs

1 551
+ Hs
+ Mm
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024