HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29511261
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1893 Hs			1 2610
+	Hs
		999205 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1199216 PB1_HUMAN (1363-1685): 4.04e-51: 201: 18.26		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1344908 BAZ1A_HUMAN (1078-1649): 3.96e-29: 130: 13.99		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1355778 BAZ1B_HUMAN (1518-1668): 6.99e-28: 125: 19.21		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		304026 TAF1_HUMAN (1-1893): 0: 2001: 100.00		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Ce
		108351 TAF1_CAEEL (167-1662): 0: 1183: 35.03		Q9GUP2_CAEEL (2359-2608): 2.04e-79: 297: 29.57
+	Hs
		164449 TRI66_HUMAN (986-1703): 3.33e-67: 253: 11.65		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Hs
		1199210 PB1_HUMAN (1363-1685): 4.04e-51: 201: 18.26		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		556698 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ANK1_HUMAN (354-913): 1.43e-61: 237: 12.27
+	Hs
		164478 TRI66_HUMAN (986-1703): 3.33e-67: 253: 11.65		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		1271460 KAT2A_HUMAN (1392-1504): 1.96e-29: 129: 29.20		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Hs
		303988 BRD1_HUMAN (1298-1540): 5.79e-31: 135: 17.48		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1350501 ZMYD8_HUMAN (1538-1629): 7.16e-13: 76.4: 36.96		HECW2_HUMAN (1360-2609): 2.26e-127: 444: 14.40
+	Sc
		765374 GCN5_YEAST (1367-1507): 1.59e-27: 119: 24.82		RSP5_YEAST (2265-2608): 2.06e-105: 360: 20.86
+	Hs
		998736 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		UBE3C_HUMAN (2405-2610): 9.09e-23: 109: 32.37
+	Hs
		1056568 BRD3_HUMAN (1394-1559): 3.22e-24: 112: 18.34		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		983172 PB1_HUMAN (1363-1685): 4.04e-51: 201: 18.26		UBE3A_HUMAN (2406-2607): 5.17e-25: 116: 34.95