HitPredict

Interactor 1: MK03 (P21708)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Interactor 2: Q8K553 (Q8K553)
FMS-related tyrosine kinase
Gene: Q8K553

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19935650
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0016310 - phosphorylation
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 380 Rn			1 129
+	At
		97545 MPK4_ARATH (9-377): 2.09e-149: 428: 47.85		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	Mm
		926397 MK01_MOUSE (29-378): 1.19e-153: 438: 87.14		FER_MOUSE (3-129): 5.64e-40: 142: 20.47
+	At
		97548 MPK16_ARATH (20-375): 9.32e-143: 418: 44.88		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	Rn
		595728 MK03_RAT (1-380): 6.6e-156: 445: 100.00		PGFRA_RAT (1-129): 2.54e-34: 127: 33.11
+	At
		97544 MPK3_ARATH (10-374): 1.23e-144: 416: 47.28		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	Rn
		600393 MK03_RAT (1-380): 6.6e-156: 445: 100.00		PGFRB_RAT (1-129): 2.99e-33: 124: 28.11
+	At
		97546 MPK6_ARATH (4-375): 3.53e-143: 413: 47.47		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	Rn
		600358 MK03_RAT (1-380): 6.6e-156: 445: 100.00		VGFR1_RAT (1-129): 2.04e-32: 121: 33.33
+	Rn
		600482 MK03_RAT (1-380): 6.6e-156: 445: 100.00		VGFR3_RAT (1-129): 1.95e-30: 116: 32.31
+	At
		96046 MPK7_ARATH (18-376): 1.16e-138: 401: 44.88		F4IAN2_ARATH (1-129): 4.36e-46: 160: 21.37
+	At
		97542 MPK1_ARATH (16-378): 8.98e-141: 406: 46.30		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	At
		97543 MPK2_ARATH (13-378): 1.63e-138: 401: 46.07		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	At
		97547 MPK7_ARATH (18-376): 1.16e-138: 401: 44.88		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	At
		97550 MPK10_ARATH (6-378): 5.19e-138: 400: 46.01		PBL23_ARATH (4-128): 2.63e-46: 155: 14.29
+	Hs
		658817 MK01_HUMAN (29-378): 1.36e-153: 438: 87.43		VGFR2_HUMAN (1-129): 4.09e-29: 112: 34.09
+	Hs
		607987 MK14_HUMAN (28-379): 2.67e-140: 404: 46.89		FGFR4_HUMAN (17-129): 6.55e-41: 145: 26.56
+	Rn
		139849 MK03_RAT (1-380): 6.6e-156: 445: 100.00		VGFR2_RAT (1-129): 3.47e-22: 92.7: 34.09