Protein: GABPA
GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60)

Gene: GABPA
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q06546

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

987758

GABP1
GA-binding protein subunit beta-1

8

6

Small-scale

0.968

High

987787

GABP2
GA-binding protein subunit beta-2

4

4

High-throughput

0.898

High

987759

EP300
Histone acetyltransferase p300

3

20

Small-scale

0.672

High

317434

YETS4
YEATS domain-containing protein 4

3

1

High-throughput

0.667

High

987767

KEAP1
Kelch-like ECH-associated protein 1

3

4

Small-scale

0.640

High

987768

FHL2
Four and a half LIM domains protein 2

2

2

Small-scale

0.619

High

692127

ELF1
ETS-related transcription factor Elf-1

1

16

High-throughput

0.618

High

781169

ETV3
ETS translocation variant 3

1

16

High-throughput

0.618

High

785357

ELK3
ETS domain-containing protein Elk-3

1

16

High-throughput

0.618

High

987757

GABPA
GA-binding protein alpha chain

1

19

Small-scale

0.618

High

987773

ELF2
ETS-related transcription factor Elf-2

1

18

High-throughput

0.618

High

987800

FEV
Protein FEV

1

17

High-throughput

0.618

High

987801

ELF4
ETS-related transcription factor Elf-4

1

18

High-throughput

0.618

High

987761

SKP2
S-phase kinase-associated protein 2

2

9

Small-scale

0.612

High

274207

STK16
Serine/threonine-protein kinase 16

2

1

High-throughput

0.606

High

435065

SP1
Transcription factor Sp1

1

20

Small-scale

0.578

High

970908

SP3
Transcription factor Sp3

1

20

Small-scale

0.578

High

202750

TPD54
Tumor protein D54

2

1

High-throughput

0.574

High

369468

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

987772

MED1
Mediator of RNA polymerase II transcription subunit 1

1

12

Small-scale

0.561

High

848200

HCFC1
Host cell factor 1

1

5

Small-scale

0.560

High

595511

ITAX
Integrin alpha-X

1

2

Small-scale

0.553

High

120080

ST2B1
Sulfotransferase 2B1

1

3

High-throughput

0.536

High

344289

AACT
Alpha-1-antichymotrypsin

1

7

High-throughput

0.536

High

396723

S10A8
Protein S100-A8

1

7

High-throughput

0.536

High

416411

S10A9
Protein S100-A9

1

8

High-throughput

0.536

High

542292

PLAK
Junction plakoglobin

1

4

High-throughput

0.536

High

638951

S100P
Protein S100-P

1

8

High-throughput

0.536

High

667952

SPB3
Serpin B3

1

6

High-throughput

0.536

High

678440

S10A7
Protein S100-A7

1

8

High-throughput

0.536

High

871539

HSP72
Heat shock-related 70 kDa protein 2

1

5

High-throughput

0.536

High

958269

ZN200
Zinc finger protein 200

1

3

High-throughput

0.536

High

987764

PKP1
Plakophilin-1

1

4

High-throughput

0.536

High

987769

GBX1
Homeobox protein GBX-1

1

16

High-throughput

0.536

High

987793

KLK6
Kallikrein-6

1

3

High-throughput

0.536

High

987806

FOXJ2
Forkhead box protein J2

1

16

High-throughput

0.536

High

987809

SPB13
Serpin B13

1

5

High-throughput

0.536

High

831256

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.527

High

987795

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.518

High

546839

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

588418

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.513

High

629113

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.513

High

666449

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.513

High

987796

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.513

High

987805

IL36G
Interleukin-36 gamma

1

0

High-throughput

0.513

High

394592

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

579140

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

7

Small-scale

0.501

High

82405

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

2

High-throughput

0.489

High

245805

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

271864

SPB7
Serpin B7

1

6

High-throughput

0.489

High

396343

APOD
Apolipoprotein D

1

2

High-throughput

0.489

High

428576

INVO
Involucrin

1

3

High-throughput

0.489

High

453960

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

High-throughput

0.489

High

608861

SPR1B
Cornifin-B

1

1

High-throughput

0.489

High

661241

S10A2
Protein S100-A2

1

8

High-throughput

0.489

High

722872

SPR1A
Cornifin-A

1

1

High-throughput

0.489

High

814371

AL1A3
Retinaldehyde dehydrogenase 3

1

1

High-throughput

0.489

High

820300

SPB4
Serpin B4

1

5

High-throughput

0.489

High

836300

KLK7
Kallikrein-7

1

2

High-throughput

0.489

High

945660

NGAL
Neutrophil gelatinase-associated lipocalin

1

3

High-throughput

0.489

High

987774

CYTM
Cystatin-M

1

1

High-throughput

0.489

High

987775

PA24E
Cytosolic phospholipase A2 epsilon

1

2

High-throughput

0.489

High

987776

KPRP
Keratinocyte proline-rich protein

1

1

High-throughput

0.489

High

987778

CORO6
Coronin-6

1

13

High-throughput

0.489

High

987783

S1A7A
Protein S100-A7A

1

8

High-throughput

0.489

High

987784

SPA9
Serpin A9

1

6

High-throughput

0.489

High

987785

PA24D
Cytosolic phospholipase A2 delta

1

2

High-throughput

0.489

High

987792

EVPL
Envoplakin

1

1

High-throughput

0.489

High

987797

TPD55
Tumor protein D55

1

1

High-throughput

0.489

High

987798

CPNS2
Calpain small subunit 2

1

1

High-throughput

0.489

High

987803

S10AE
Protein S100-A14

1

7

High-throughput

0.489

High

987812

FCGBP
IgGFc-binding protein

1

2

High-throughput

0.489

High

174822

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

177274

HDAC3
Histone deacetylase 3

1

7

Small-scale

0.479

High

179613

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.479

High

227252

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

316863

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

346605

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

569638

CEBPB
CCAAT/enhancer-binding protein beta

1

9

Small-scale

0.479

High

575398

EGR1
Early growth response protein 1

1

8

High-throughput

0.479

High

632703

TYY1
Transcriptional repressor protein YY1

1

10

Small-scale

0.479

High

823921

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

884137

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

934690

H31
Histone H3.1

1

12

High-throughput

0.479

High

952291

H33
Histone H3.3

1

12

High-throughput

0.479

High

987760

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

987762

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.479

High

987763

HDAC1
Histone deacetylase 1

1

7

Small-scale

0.479

High

987765

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

987770

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

987786

NUP43
Nucleoporin Nup43

1

10

High-throughput

0.479

High

987788

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

987791

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

987794

LHX4
LIM/homeobox protein Lhx4

1

6

High-throughput

0.479

High

987802

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

987807

LHX3
LIM/homeobox protein Lhx3

1

6

High-throughput

0.479

High

987810

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

987811

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

672954

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

1

Small-scale

0.470

High

651029

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

720296

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

987771

ELOB
Elongin-B

1

0

High-throughput

0.458

High

72288

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

798233

KI3L1
Killer cell immunoglobulin-like receptor 3DL1

1

2

Small-scale

0.437

High

987780

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

66388

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

353517

IGKC
Immunoglobulin kappa constant

1

2

High-throughput

0.407

High

353662

IGHG1
Immunoglobulin heavy constant gamma 1

1

2

High-throughput

0.407

High

987777

ZC21B
Zinc finger C2HC domain-containing protein 1B

2

0

High-throughput

0.316

High

987766

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

0

Small-scale

0.305

High

259843

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

519681

ANXA3
Annexin A3

1

0

High-throughput

0.279

Low

572122

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

611234

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

648493

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

987779

ACP7
Acid phosphatase type 7

1

0

High-throughput

0.279

Low

987781

FBX50
F-box only protein 50

1

0

High-throughput

0.279

Low

987782

GDPD3
Lysophospholipase D GDPD3

1

0

High-throughput

0.279

Low

987789

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

987790

CV015
Uncharacterized protein C22orf15

1

0

High-throughput

0.279

Low

987799

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

987804

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.279

Low

987808

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

225264

AGRB2
Adhesion G protein-coupled receptor B2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024