HitPredict

Interactor 1: UBC1 (P21734)
Ubiquitin-conjugating enzyme E2 1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 1) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-24 kDa) (Ubiquitin-protein ligase)
Gene: UBC1

Interactor 2: UBA4 (P38820)
Adenylyltransferase and sulfurtransferase UBA4 (Needs CLA4 to survive protein 3) (Ubiquitin-like protein activator 4) [Includes: Adenylyltransferase UBA4 (EC 2.7.7.-); Sulfurtransferase UBA4 (EC 2.8.1.-)]
Gene: UBA4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9388185
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Sc			1 440
+	Hs
		919856 UB2D2_HUMAN (2-150): 1.55e-76: 228: 44.97		UBA5_HUMAN (4-275): 9.09e-65: 215: 20.67
+	Hs
		919796 UB2D2_HUMAN (2-150): 1.55e-76: 228: 44.97		UBA3_HUMAN (1-230): 6.63e-62: 209: 23.58
+	Sp
		251976 UBC1_SCHPO (1-214): 5.92e-76: 229: 52.75		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Sp
		293848 UBC4_SCHPO (2-149): 3.24e-75: 225: 43.24		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Sp
		142467 UBC13_SCHPO (1-149): 3.34e-68: 207: 40.27		UBA1_SCHPO (43-358): 2.11e-57: 205: 15.17
+	Hs
		1282360 UB2E3_HUMAN (2-150): 5.53e-69: 211: 42.95		SAE2_HUMAN (51-226): 3.88e-57: 200: 25.42
+	Sc
		600919 UBC1_YEAST (1-215): 1.33e-82: 246: 100.00		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		607190 UB2D4_HUMAN (2-150): 2.65e-77: 230: 45.64		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607050 UB2D2_HUMAN (2-150): 1.55e-76: 228: 44.97		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607026 UB2D1_HUMAN (2-150): 2.39e-76: 227: 44.97		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607039 UB2D3_HUMAN (2-150): 2.28e-75: 225: 43.62		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Sc
		549788 UBC4_YEAST (1-149): 9.98e-77: 229: 44.97		UBA1_YEAST (33-418): 9.78e-41: 157: 15.29
+	Hs
		607129 UB2E3_HUMAN (2-150): 5.53e-69: 211: 42.95		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607136 UB2E2_HUMAN (2-150): 3.32e-69: 211: 42.28		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607028 UB2E1_HUMAN (2-150): 1.64e-68: 209: 42.95		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607054 UBE2B_HUMAN (1-147): 1.29e-65: 200: 36.91		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607023 UBE2A_HUMAN (1-147): 5.72e-65: 199: 37.58		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Hs
		607042 UBE2N_HUMAN (4-150): 3.58e-64: 197: 41.50		UBA1_HUMAN (17-377): 2.17e-43: 164: 14.36
+	Dm
		715098 UBE2N_DROME (2-151): 4.72e-69: 209: 38.00		Q8T0L3_DROME (43-358): 2.27e-27: 117: 13.23
+	Hs
		782203 UB2E1_HUMAN (2-150): 1.64e-68: 209: 42.95		UBA7_HUMAN (46-200): 2.1e-09: 62: 32.93