HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 821 Hs			1 869
+	Hs
		601480 FGFR2_HUMAN (1-821): 0: 863: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		508270 FGFR1_HUMAN (1-820): 0: 772: 71.17		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		507913 FGFR1_HUMAN (1-820): 0: 772: 71.17		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		609615 FGFR3_HUMAN (10-821): 0: 731: 65.69		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		609215 FGFR3_HUMAN (10-821): 0: 731: 65.69		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		608198 FGFR4_HUMAN (22-810): 0: 684: 55.86		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		607921 FGFR4_HUMAN (22-810): 0: 684: 55.86		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		384503 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		384691 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Hs
		128396 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		DNM1L_HUMAN (6-750): 0: 788: 38.25
+	Hs
		572603 VGFR1_HUMAN (5-134): 1.03e-11: 70.9: 16.42		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		729628 VGFR2_HUMAN (46-363): 1.44e-11: 70.5: 16.82		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		231041 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		OPA1_HUMAN (7-660): 1.13e-158: 490: 19.02