Interactor 1: IDHP (P21954)
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDP1

Interactor 2: IDH2 (P28241)
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
Gene: IDH2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Iso_dh~Iso_dh
Common GO terms GO:0000287 - magnesium ion binding
GO:0005739 - mitochondrion
GO:0006099 - tricarboxylic acid cycle
GO:0006102 - isocitrate metabolic process
GO:0006537 - glutamate biosynthetic process
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 428
Sc

1 369
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024