Protein: CDK1
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 2) (Cell division protein kinase 1) (p34 protein kinase)

Gene: CDK1, cdc2
Organism: Schizosaccharomyces pombe 972h-
Interactions: 51
UniProt ID: P04551

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000776 - kinetochore
GO:0000785 - chromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

410432

CKS1
Cyclin-dependent kinases regulatory subunit

5

20

Small-scale

0.914

High

410438

CHK1
Serine/threonine-protein kinase chk1

2

2

Small-scale

0.789

High

238068

FKH2
Fork head protein homolog 2

2

7

Small-scale

0.778

High

410463

FLP1
Tyrosine-protein phosphatase CDC14 homolog

2

5

Small-scale

0.778

High

410440

CG22
G2/mitotic-specific cyclin cig2

2

20

Small-scale

0.776

High

410435

PUC1
Cyclin puc1

2

20

Small-scale

0.754

High

267895

CG1C
Cyclin pch1

1

20

Small-scale

0.740

High

410442

RUM1
Cyclin-dependent kinase inhibitor rum1

5

0

Small-scale

0.690

High

410433

PP11
Serine/threonine-protein phosphatase PP1-1

4

10

Small-scale

0.685

High

314826

CDC37
Hsp90 co-chaperone Cdc37

1

5

Small-scale

0.665

High

314922

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase bub1

1

19

Small-scale

0.647

High

410431

MPIP
M-phase inducer phosphatase

1

17

Small-scale

0.647

High

410436

MIK1
Mitosis inhibitor protein kinase mik1

1

19

Small-scale

0.647

High

410458

CRK1
Serine/threonine-protein kinase crk1

1

17

Small-scale

0.647

High

410451

ORC2
Origin recognition complex subunit 2

2

6

Small-scale

0.636

High

410444

CDC18
Cell division control protein 18

2

11

Small-scale

0.629

High

267732

CDC11
Septation initiation network scaffold protein cdc11

1

1

Small-scale

0.618

High

410434

CG21
G2/mitotic-specific cyclin cig1

1

20

Small-scale

0.618

High

410441

HHP1
Casein kinase I homolog hhp1

1

5

Small-scale

0.618

High

410445

HSP90
Heat shock protein 90 homolog

1

15

Small-scale

0.618

High

410446

STE20
Serine/threonine-protein kinase shk1/pak1

1

9

Small-scale

0.618

High

410448

CGP1
G1/S-specific cyclin pas1

1

20

Small-scale

0.618

High

410465

GAD8
Serine/threonine-protein kinase gad8

1

8

Small-scale

0.618

High

410449

RHP9
DNA repair protein crb2

2

0

Small-scale

0.577

High

410460

NSK1
Kinetochore protein nsk1

1

4

Small-scale

0.561

High

153470

SLD2
DNA replication regulator sld2

1

0

Small-scale

0.537

High

410453

SDS23
Protein sds23/moc1

1

1

Small-scale

0.527

High

207040

MBX1
MADS-box transcription factor 1

1

2

Small-scale

0.501

High

410437

PYP3
Tyrosine-protein phosphatase 3

1

3

Small-scale

0.501

High

410443

SMC4
Structural maintenance of chromosomes protein 4

1

6

Small-scale

0.501

High

410459

KLP9
Kinesin-like motor protein 9

1

4

Small-scale

0.501

High

410461

ASE1
Anaphase spindle elongation protein 1

1

8

Small-scale

0.501

High

151966

HCN1
Anaphase-promoting complex subunit hcn1

1

0

Small-scale

0.480

High

207231

MDE4
Monopolin complex subunit mde4

1

0

Small-scale

0.480

High

237663

CUT12
Spindle pole body-associated protein cut12

1

0

Small-scale

0.480

High

410456

BYR4
Protein byr4

1

0

Small-scale

0.480

High

410464

NHEJ1
Xrcc4-like factor 1

1

0

Small-scale

0.480

High

410466

ALP7
Microtubule protein alp7

1

0

Small-scale

0.480

High

151523

YE02
Uncharacterized helicase C17H9.02

1

8

High-throughput

0.479

High

313753

PIR2
NURS complex subunit pir2

1

1

High-throughput

0.479

High

314048

KU70
ATP-dependent DNA helicase II subunit 1

1

7

Small-scale

0.479

High

410439

RAD16
DNA repair protein rad16

1

1

Small-scale

0.479

High

410447

SKB1
Protein arginine N-methyltransferase skb1

1

4

Small-scale

0.479

High

410450

MUS81
Crossover junction endonuclease mus81

1

1

Small-scale

0.479

High

410452

HUS2
ATP-dependent DNA helicase hus2/rqh1

1

9

Small-scale

0.479

High

410454

SRS2
ATP-dependent DNA helicase srs2

1

3

Small-scale

0.479

High

410457

WOS2
Protein wos2

1

1

Small-scale

0.479

High

410462

KU80
ATP-dependent DNA helicase II subunit 2

1

7

Small-scale

0.479

High

410467

RED1
NURS complex subunit red1

1

1

High-throughput

0.479

High

268550

CBF11
Transcription factor cbf11

1

0

High-throughput

0.458

High

410455

SPD1
S-phase delaying protein 1

1

0

Small-scale

0.458

High


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Last updated: 11Aug2025