HitPredict

Interactor 1: TAL1 (P22091)
T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein)
Gene: TAL1

Interactor 2: RBTN2 (P25801)
Rhombotin-2 (Cysteine-rich protein TTG-2) (LIM domain only protein 2) (LMO-2) (T-cell translocation protein 2)
Gene: Lmo2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	21186366, 19799863, 16407974
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0032991 - protein-containing complex GO:0035162 - embryonic hemopoiesis GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 329 Mm			1 158
+	Hs
		568179 TAL1_HUMAN (1-329): 5.52e-86: 263: 92.15		RBTN2_HUMAN (1-158): 3.41e-42: 139: 99.37
+	Mm
		604035 TAL1_MOUSE (1-329): 5.69e-89: 271: 100.00		LMO3_MOUSE (30-156): 1.69e-38: 129: 58.27
+	Hs
		568180 TAL1_HUMAN (1-329): 5.52e-86: 263: 92.15		RBTN1_HUMAN (11-150): 7.46e-40: 133: 52.86
+	Hs
		1148470 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX8_HUMAN (24-148): 1.03e-47: 159: 33.60
+	Hs
		524537 LYL1_HUMAN (95-299): 3.82e-28: 112: 43.60		RBTN2_HUMAN (1-158): 3.41e-42: 139: 99.37
+	Hs
		524538 LYL1_HUMAN (95-299): 3.82e-28: 112: 43.60		RBTN1_HUMAN (11-150): 7.46e-40: 133: 52.86
+	Hs
		638295 TAL2_HUMAN (186-297): 1.68e-27: 105: 46.43		RBTN2_HUMAN (1-158): 3.41e-42: 139: 99.37
+	Hs
		1163324 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX6_HUMAN (7-153): 1.01e-37: 133: 27.70
+	Hs
		638508 TAL2_HUMAN (186-297): 1.68e-27: 105: 46.43		RBTN1_HUMAN (11-150): 7.46e-40: 133: 52.86
+	Mm
		1143747 TAL2_MOUSE (186-297): 1.59e-27: 105: 48.21		RBTN1_MOUSE (11-150): 1.69e-39: 132: 52.86
+	Hs
		210862 TCF21_HUMAN (155-267): 3.22e-27: 106: 34.48		LMO4_HUMAN (11-147): 8.07e-39: 131: 42.34
+	Mm
		1143746 TAL2_MOUSE (186-297): 1.59e-27: 105: 48.21		LMO3_MOUSE (30-156): 1.69e-38: 129: 58.27
+	Hs
		638265 HEN1_HUMAN (189-244): 1.03e-21: 91: 60.71		RBTN2_HUMAN (1-158): 3.41e-42: 139: 99.37
+	Dm
		114761 Q9VHG3_DROME (96-273): 2.44e-27: 109: 22.91		M9PD53_DROME (2-86): 4.82e-15: 73.1: 17.44
+	Dm
		80870 DIMM_DROME (127-326): 1.57e-29: 118: 20.10		APTE_DROME (94-155): 1.46e-11: 63: 20.97
+	Hs
		1163323 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX3_HUMAN (92-155): 1.77e-12: 65.3: 23.44
+	Dm
		1359764 Q9VHG3_DROME (96-273): 2.44e-27: 109: 22.91		Q9V472_DROME (94-155): 1.31e-09: 57.3: 22.58
+	Dm
		1368265 Q9W4I4_DROME (189-244): 2.87e-21: 90.6: 57.14		Q9VJ00_DROME (2-86): 6.84e-15: 72.7: 17.44
+	Dm
		112565 Q9W4I4_DROME (189-244): 2.87e-21: 90.6: 57.14		M9NCY1_DROME (89-155): 6.6e-10: 58: 17.91