HitPredict

Interactor 1: TAL1 (P22091)
T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein)
Gene: TAL1

Interactor 2: LMO3 (Q8BZL8)
LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1)
Gene: LMO3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 329 Mm			1 145
+	Mm
		603898 TAL1_MOUSE (1-329): 5.69e-89: 271: 100.00		RBTN2_MOUSE (13-133): 5.98e-46: 148: 60.33
+	Hs
		568179 TAL1_HUMAN (1-329): 5.52e-86: 263: 92.15		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		568180 TAL1_HUMAN (1-329): 5.52e-86: 263: 92.15		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		1148470 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX8_HUMAN (12-132): 3.05e-46: 155: 39.67
+	Hs
		524537 LYL1_HUMAN (95-299): 3.82e-28: 112: 43.60		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		1163324 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX6_HUMAN (3-137): 8.85e-42: 143: 36.30
+	Hs
		638295 TAL2_HUMAN (186-297): 1.68e-27: 105: 46.43		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Dm
		80870 DIMM_DROME (127-326): 1.57e-29: 118: 20.10		APTE_DROME (13-131): 4.75e-37: 133: 38.66
+	Hs
		210862 TCF21_HUMAN (155-267): 3.22e-27: 106: 34.48		LMO4_HUMAN (11-142): 3.16e-41: 136: 50.76
+	Hs
		638265 HEN1_HUMAN (189-244): 1.03e-21: 91: 60.71		RBTN2_HUMAN (13-133): 8.21e-46: 148: 60.33
+	Hs
		524538 LYL1_HUMAN (95-299): 3.82e-28: 112: 43.60		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Mm
		1143746 TAL2_MOUSE (186-297): 1.59e-27: 105: 48.21		LMO3_MOUSE (1-145): 3.61e-37: 125: 100.00
+	Mm
		1143747 TAL2_MOUSE (186-297): 1.59e-27: 105: 48.21		RBTN1_MOUSE (1-133): 8.13e-37: 125: 95.49
+	Hs
		638508 TAL2_HUMAN (186-297): 1.68e-27: 105: 46.43		RBTN1_HUMAN (1-133): 5.2e-37: 125: 95.49
+	Hs
		1163323 FIGLA_HUMAN (120-305): 4.51e-28: 110: 21.47		LHX3_HUMAN (4-68): 2.41e-11: 61.9: 21.21
+	Dm
		1359764 Q9VHG3_DROME (96-273): 2.44e-27: 109: 22.91		Q9V472_DROME (72-144): 2.17e-11: 61.9: 21.92
+	Dm
		114761 Q9VHG3_DROME (96-273): 2.44e-27: 109: 22.91		M9PD53_DROME (72-142): 4.55e-11: 61.1: 19.72
+	Dm
		1368265 Q9W4I4_DROME (189-244): 2.87e-21: 90.6: 57.14		Q9VJ00_DROME (72-142): 6.42e-11: 60.8: 19.72
+	Dm
		112565 Q9W4I4_DROME (189-244): 2.87e-21: 90.6: 57.14		M9NCY1_DROME (4-69): 2.38e-10: 58.8: 22.39