HitPredict

Interactor 1: XRN1 (P22147)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (DNA strand transfer protein beta) (STP-beta) (KAR(-)-enhancing mutation protein) (Strand exchange protein 1) (p175)
Gene: XRN1

Interactor 2: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.666

Property	Details
Experiments	10900456, 9207794, 16554755
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006364 - rRNA processing
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1528 Sc			1 109
+	Sc
		605080 XRN1_YEAST (1-1528): 0: 2262: 100.00		LSM1_YEAST (2-108): 1.12e-29: 106: 20.18
+	Sc
		605109 XRN1_YEAST (1-1528): 0: 2262: 100.00		LSM7_YEAST (5-71): 3.29e-13: 62.3: 15.00
+	Sc
		605117 XRN1_YEAST (1-1528): 0: 2262: 100.00		LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22
+	Hs
		167704 XRN1_HUMAN (1-1257): 0: 1556: 33.64		LSM1_HUMAN (2-102): 1.21e-28: 102: 21.70