Protein: CYH1
Cytohesin-1 (PH, SEC7 and coiled-coil domain-containing protein 1) (SEC7 homolog B2-1)

Gene: CYH1, CYTH1
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q15438

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149055

ICEF1
Interactor protein for cytohesin exchange factors 1

5

18

Small-scale

0.930

High

1149057

CNKR1
Connector enhancer of kinase suppressor of ras 1

4

18

High-throughput

0.902

High

1149049

ITSN1
Intersectin-1

2

7

High-throughput

0.791

High

255523

CYTIP
Cytohesin-interacting protein

7

17

Small-scale

0.747

High

1149050

INAVA
Innate immunity activator protein

6

11

Small-scale

0.734

High

424082

ITB2
Integrin beta-2

4

1

Small-scale

0.696

High

225479

CYH3
Cytohesin-3

1

9

High-throughput

0.691

High

1149061

CYH2
Cytohesin-2

1

9

High-throughput

0.691

High

783276

TRI23
E3 ubiquitin-protein ligase TRIM23

1

18

Small-scale

0.680

High

1117326

ARFRP
ADP-ribosylation factor-related protein 1

1

20

Small-scale

0.680

High

728253

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.665

High

1149059

CC120
Coiled-coil domain-containing protein 120

5

11

High-throughput

0.653

High

975048

ARF6
ADP-ribosylation factor 6

1

14

Small-scale

0.647

High

1149051

CCD40
Coiled-coil domain-containing protein 40

2

3

High-throughput

0.628

High

1140318

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.618

High

1149060

SNX27
Sorting nexin-27

1

13

Small-scale

0.618

High

299828

SNPC5
snRNA-activating protein complex subunit 5

3

2

High-throughput

0.607

High

966344

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

396173

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

882495

ARRB1
Beta-arrestin-1

1

3

Small-scale

0.561

High

893489

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

4

Small-scale

0.561

High

584097

FOSL2
Fos-related antigen 2

2

7

High-throughput

0.553

High

340134

PCNT
Pericentrin

1

4

High-throughput

0.541

High

166525

BACH1
Transcription regulator protein BACH1

1

1

High-throughput

0.536

High

167513

TX1B3
Tax1-binding protein 3

1

10

High-throughput

0.536

High

239064

ZNRD2
Protein ZNRD2

1

2

High-throughput

0.536

High

290008

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.536

High

506949

POTEI
POTE ankyrin domain family member I

1

1

High-throughput

0.536

High

987363

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

High-throughput

0.536

High

1098550

GPS2
G protein pathway suppressor 2

1

1

High-throughput

0.536

High

1149052

P5CR3
Pyrroline-5-carboxylate reductase 3

1

2

High-throughput

0.536

High

1149062

BACH2
Transcription regulator protein BACH2

1

2

High-throughput

0.536

High

1149066

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

6

High-throughput

0.536

High

1149067

FRM4A
FERM domain-containing protein 4A

1

11

High-throughput

0.536

High

1149069

FRM4B
FERM domain-containing protein 4B

1

15

High-throughput

0.536

High

1149070

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

461506

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.515

High

1149068

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.515

High

549596

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

1149063

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.513

High

660266

BDNF
Neurotrophic factor BDNF precursor form

1

0

High-throughput

0.493

High

771887

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.493

High

1149056

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.493

High

1149058

APH1A
Gamma-secretase subunit APH-1A

1

0

High-throughput

0.493

High

1149065

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.493

High

429942

JUN
Transcription factor Jun

1

1

High-throughput

0.489

High

605081

JUND
Transcription factor JunD

1

1

High-throughput

0.489

High

1149053

SYCE1
Synaptonemal complex central element protein 1

1

2

High-throughput

0.489

High

732605

ARRB2
Beta-arrestin-2

1

3

Small-scale

0.479

High

904755

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

872356

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1149054

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1149064

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High


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Last updated: 11Aug2025