Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA
Interactor 2: DRD1 (P21728)
D(1A) dopamine receptor (Dopamine D1 receptor)
Gene: DRD1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7609904 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0098978 - glutamatergic synapse |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
