Protein: KAPCA
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)

Gene: KAPCA, Prkaca
Organism: Mus musculus
Interactions: 36
UniProt ID: P05132

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000287 - magnesium ion binding
GO:0001669 - acrosomal vesicle
GO:0001707 - mesoderm formation
GO:0001843 - neural tube closure

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

424697

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

5

20

Small-scale

0.944

High

424706

IPKA
cAMP-dependent protein kinase inhibitor alpha

3

2

Small-scale

0.858

High

424708

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.691

High

424711

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

5

High-throughput

0.691

High

424695

SRC
Proto-oncogene tyrosine-protein kinase Src

1

16

Small-scale

0.647

High

424698

ADRB1
Beta-1 adrenergic receptor

1

1

Small-scale

0.618

High

424702

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

8

High-throughput

0.618

High

424716

TRPV1
Transient receptor potential cation channel subfamily V member 1

1

1

Small-scale

0.618

High

424721

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

18

Small-scale

0.618

High

424723

GSK3B
Glycogen synthase kinase-3 beta

1

19

Small-scale

0.618

High

424696

TAU
Microtubule-associated protein tau

2

15

Small-scale

0.595

High

424722

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed]

1

20

Small-scale

0.590

High

424713

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

Small-scale

0.575

High

424712

Q3UIK0
Myosin-binding protein C, cardiac-type

1

0

Small-scale

0.541

High

424699

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

6

High-throughput

0.536

High

266666

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

Small-scale

0.501

High

424700

VATA
V-type proton ATPase catalytic subunit A

1

6

Small-scale

0.501

High

424710

SOX9
Transcription factor SOX-9

1

6

Small-scale

0.501

High

424715

LASP1
LIM and SH3 domain protein 1

1

9

Small-scale

0.501

High

424719

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

1

Small-scale

0.501

High

424705

PPLA
Phospholamban

1

0

Small-scale

0.481

High

92618

AKAP5
A-kinase anchor protein 5

1

6

Small-scale

0.481

High

408243

MBP
Myelin basic protein

1

0

Small-scale

0.480

High

424707

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

1

0

Small-scale

0.480

High

108389

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

424701

HXK4
Hexokinase-4

1

3

Small-scale

0.479

High

424703

ATX1
Ataxin-1

1

3

High-throughput

0.479

High

424709

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

6

High-throughput

0.479

High

424714

BAD
Bcl2-associated agonist of cell death

1

4

Small-scale

0.479

High

424717

RSBN1
Lysine-specific demethylase 9

1

1

Small-scale

0.479

High

424720

PARK7
Parkinson disease protein 7 homolog

1

1

Small-scale

0.479

High

424704

EVC
EvC complex member EVC

1

0

Small-scale

0.458

High

424718

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.458

High

98308

E9QJV1
Fibrous sheath CABYR binding protein

1

2

Small-scale

0.457

High

117777

M0QW46
Achaete-scute family bHLH transcription factor 4

1

3

Small-scale

0.457

High

424724

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

9

Small-scale

0.445

High


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Last updated: 11Aug2025