HitPredict

Interactor 1: VPS15 (P22219)
Serine/threonine-protein kinase VPS15 (EC 2.7.11.1) (Golgi-retention defective mutant protein 8) (Vacuolar protein sorting-associated protein 15)
Gene: VPS15

Interactor 2: BECN1 (Q02948)
Vacuolar protein sorting-associated protein 30 (Autophagy-related protein 6)
Gene: VPS30

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

The method score is based on:

Property	Details
Experiments	23904270, 16429126, 16421251, 37968396, 11157979
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0000329 - fungal-type vacuole membrane GO:0000425 - pexophagy GO:0006623 - protein targeting to vacuole GO:0006914 - autophagy and 8 others more... GO:0010008 - endosome membrane GO:0016236 - macroautophagy GO:0034045 - phagophore assembly site membrane GO:0034271 - phosphatidylinositol 3-kinase complex, class III, type I GO:0034272 - phosphatidylinositol 3-kinase complex, class III, type II GO:0045324 - late endosome to vacuole transport GO:0046854 - phosphatidylinositol phosphate biosynthetic process GO:0120095 - vacuole-isolation membrane contact site
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	1454
Sc

1	557

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024