Protein: PEBP1
Phosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) (Neuropolypeptide h3) (Prostatic-binding protein) (Raf kinase inhibitor protein) (RKIP) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)]

Gene: PEBP1
Organism: Homo sapiens
Interactions: 208
UniProt ID: P30086

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

400347

RAF1
RAF proto-oncogene serine/threonine-protein kinase

7

4

Small-scale

0.753

High

717246

1433B
14-3-3 protein beta/alpha

2

8

High-throughput

0.737

High

717247

1433S
14-3-3 protein sigma

2

8

High-throughput

0.737

High

715442

MARCS
Myristoylated alanine-rich C-kinase substrate

4

1

High-throughput

0.672

High

717242

PEBP1
Phosphatidylethanolamine-binding protein 1

1

2

High-throughput

0.618

High

213829

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

1

Small-scale

0.611

High

717307

STK38
Serine/threonine-protein kinase 38

2

2

High-throughput

0.611

High

599545

STMN1
Stathmin

3

0

High-throughput

0.606

High

717361

ATIF1
ATPase inhibitor, mitochondrial

3

0

High-throughput

0.606

High

717353

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

410649

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

3

High-throughput

0.576

High

187896

EIF3H
Eukaryotic translation initiation factor 3 subunit H

2

3

High-throughput

0.571

High

361525

CERU
Ceruloplasmin

2

1

High-throughput

0.571

High

402862

ANXA1
Annexin A1

2

5

High-throughput

0.571

High

415375

HSPB1
Heat shock protein beta-1

2

1

High-throughput

0.571

High

445133

S10A6
Protein S100-A6

2

3

High-throughput

0.571

High

456625

ANXA2
Annexin A2

2

5

High-throughput

0.571

High

489075

ALDOC
Fructose-bisphosphate aldolase C

2

1

High-throughput

0.571

High

553125

KCRB
Creatine kinase B-type

2

1

High-throughput

0.571

High

577634

PLAK
Junction plakoglobin

2

1

High-throughput

0.571

High

658636

JAK1
Tyrosine-protein kinase JAK1

2

1

High-throughput

0.571

High

686781

S10A4
Protein S100-A4

2

3

High-throughput

0.571

High

698414

CALX
Calnexin

2

2

High-throughput

0.571

High

710080

EPHA2
Ephrin type-A receptor 2

2

3

High-throughput

0.571

High

717249

GLYM
Serine hydroxymethyltransferase, mitochondrial

2

1

High-throughput

0.571

High

717259

MDHM
Malate dehydrogenase, mitochondrial

2

3

High-throughput

0.571

High

717267

GDIB
Rab GDP dissociation inhibitor beta

2

1

High-throughput

0.571

High

717268

SERPH
Serpin H1

2

3

High-throughput

0.571

High

717275

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

1

High-throughput

0.571

High

717278

CH10
10 kDa heat shock protein, mitochondrial

2

2

High-throughput

0.571

High

717281

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

2

9

High-throughput

0.571

High

717288

DSG1
Desmoglein-1

2

1

High-throughput

0.571

High

717298

PTK7
Inactive tyrosine-protein kinase 7

2

2

High-throughput

0.571

High

717305

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

1

High-throughput

0.571

High

717312

F263
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

2

3

High-throughput

0.571

High

717342

RIOK1
Serine/threonine-protein kinase RIO1

2

2

High-throughput

0.571

High

717347

CYBP
Calcyclin-binding protein

2

2

High-throughput

0.571

High

717260

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

190195

MOT4
Monocarboxylate transporter 4

2

0

High-throughput

0.547

High

290869

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.547

High

391126

HEMO
Hemopexin

2

0

High-throughput

0.547

High

420385

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

2

0

High-throughput

0.547

High

442243

GELS
Gelsolin

2

0

High-throughput

0.547

High

587565

DESP
Desmoplakin

2

0

High-throughput

0.547

High

596607

NCPR
NADPH--cytochrome P450 reductase

2

0

High-throughput

0.547

High

601571

HMGA1
High mobility group protein HMG-I/HMG-Y

2

0

High-throughput

0.547

High

683582

ITA3
Integrin alpha-3

2

0

High-throughput

0.547

High

717244

METK2
S-adenosylmethionine synthase isoform type-2

2

0

High-throughput

0.547

High

717254

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

2

0

High-throughput

0.547

High

717264

CD151
CD151 antigen

2

0

High-throughput

0.547

High

717265

FAS
Fatty acid synthase

2

0

High-throughput

0.547

High

717269

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

2

0

High-throughput

0.547

High

717282

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

0

High-throughput

0.547

High

717295

LMAN2
Vesicular integral-membrane protein VIP36

2

0

High-throughput

0.547

High

717321

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

2

0

High-throughput

0.547

High

717345

BOLA2
BolA-like protein 2

2

0

High-throughput

0.547

High

717349

MAGE1
Melanoma-associated antigen E1

2

0

High-throughput

0.547

High

717350

RAB18
Ras-related protein Rab-18

2

0

High-throughput

0.547

High

717356

ARGL1
Arginine and glutamate-rich protein 1

2

0

High-throughput

0.547

High

717357

CWC25
Pre-mRNA-splicing factor CWC25 homolog

2

0

High-throughput

0.547

High

717363

ACSL5
Long-chain-fatty-acid--CoA ligase 5

2

0

High-throughput

0.547

High

717370

NS1BP
Influenza virus NS1A-binding protein

2

0

High-throughput

0.547

High

180719

TIF1A
Transcription intermediary factor 1-alpha

1

2

High-throughput

0.536

High

529167

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

717252

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

6

High-throughput

0.536

High

717292

KPCZ
Protein kinase C zeta type

1

7

High-throughput

0.536

High

717294

MERTK
Tyrosine-protein kinase Mer

1

5

High-throughput

0.536

High

717319

MYLK4
Myosin light chain kinase family member 4

1

2

High-throughput

0.536

High

717326

STYX
Serine/threonine/tyrosine-interacting protein

1

1

Small-scale

0.536

High

717333

LMTK3
Serine/threonine-protein kinase LMTK3

1

3

High-throughput

0.536

High

717344

KPCD2
Serine/threonine-protein kinase D2

1

4

High-throughput

0.536

High

240060

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

1

High-throughput

0.521

High

350582

TXD12
Thioredoxin domain-containing protein 12

2

1

High-throughput

0.521

High

717365

TMED5
Transmembrane emp24 domain-containing protein 5

2

1

High-throughput

0.521

High

302246

STC2
Stanniocalcin-2

1

0

High-throughput

0.518

High

684935

DNMT1
DNA

1

0

High-throughput

0.518

High

590984

LOX15
Polyunsaturated fatty acid lipoxygenase ALOX15

1

0

Small-scale

0.513

High

717261

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

717306

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

717324

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

578394

BRAF
Serine/threonine-protein kinase B-raf

1

4

Small-scale

0.501

High

717289

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

6

Small-scale

0.501

High

477213

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

4

High-throughput

0.500

High

710673

EPHA8
Ephrin type-A receptor 8

1

4

High-throughput

0.500

High

717290

TIE2
Angiopoietin-1 receptor

1

5

High-throughput

0.500

High

635166

HNF1A
Hepatocyte nuclear factor 1-alpha

1

0

Small-scale

0.493

High

717366

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.493

High

717340

NKX31
Homeobox protein Nkx-3.1

1

1

Small-scale

0.481

High

703449

MK01
Mitogen-activated protein kinase 1

1

0

Small-scale

0.480

High

167830

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

Small-scale

0.479

High

169967

AURKA
Aurora kinase A

1

2

High-throughput

0.479

High

347546

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

365310

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.479

High

425338

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.479

High

476096

ANXA5
Annexin A5

1

5

High-throughput

0.479

High

566570

PDIA4
Protein disulfide-isomerase A4

1

5

High-throughput

0.479

High

587993

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

606288

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

616139

PGAM1
Phosphoglycerate mutase 1

1

3

High-throughput

0.479

High

656046

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

3

High-throughput

0.479

High

669105

ARBK1
Beta-adrenergic receptor kinase 1

1

2

Small-scale

0.479

High

697776

CALR
Calreticulin

1

2

High-throughput

0.479

High

712135

TKT
Transketolase

1

1

High-throughput

0.479

High

716493

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

4

High-throughput

0.479

High

717243

PDIA3
Protein disulfide-isomerase A3

1

5

High-throughput

0.479

High

717245

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.479

High

717251

BASI
Basigin

1

1

High-throughput

0.479

High

717257

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.479

High

717279

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.479

High

717280

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

717286

FKBP3
Peptidyl-prolyl cis-trans isomerase FKBP3

1

8

High-throughput

0.479

High

717296

FOXC1
Forkhead box protein C1

1

3

High-throughput

0.479

High

717297

PAK2
Serine/threonine-protein kinase PAK 2

1

3

High-throughput

0.479

High

717300

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

717302

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

717309

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.479

High

717313

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.479

High

717318

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

717328

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

717329

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.479

High

717330

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.479

High

717332

SCLT1
Sodium channel and clathrin linker 1

1

1

High-throughput

0.479

High

717338

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

3

Small-scale

0.479

High

717339

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

717346

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.479

High

717352

SAR1A
Small COPII coat GTPase SAR1A

1

2

High-throughput

0.479

High

717359

EPHA6
Ephrin type-A receptor 6

1

3

High-throughput

0.479

High

717360

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

164261

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

178191

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

259501

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

361132

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

369837

CO3
Complement C3

1

0

High-throughput

0.458

High

379898

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

424361

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

447686

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.458

High

459474

PROF1
Profilin-1

1

0

High-throughput

0.458

High

538886

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

557886

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

570845

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

599161

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

635781

PTMS
Parathymosin

1

0

High-throughput

0.458

High

667565

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

694703

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

699604

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.458

High

717253

8ODP
Oxidized purine nucleoside triphosphate hydrolase

1

0

Small-scale

0.458

High

717255

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

717256

COIL
Coilin

1

0

High-throughput

0.458

High

717258

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

717262

RFX5
DNA-binding protein RFX5

1

0

High-throughput

0.458

High

717263

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

717271

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

717276

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

717277

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

717284

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

717285

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

717293

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

717299

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

717301

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

717303

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

717304

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

717310

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

717314

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

717320

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

717322

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

717325

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

717327

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

717335

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

717336

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.458

High

717337

DNJC2
DnaJ homolog subfamily C member 2

1

0

High-throughput

0.458

High

717341

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

717351

PODO
Podocin

1

0

High-throughput

0.458

High

717354

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.458

High

717358

TRM7
tRNA

1

0

High-throughput

0.458

High

717362

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

0

High-throughput

0.458

High

717368

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

66990

AXA2L
Putative annexin A2-like protein

1

5

High-throughput

0.445

High

717270

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

717272

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

717311

NF2L2
Nuclear factor erythroid 2-related factor 2

1

1

High-throughput

0.445

High

717316

NEK10
Serine/threonine-protein kinase Nek10

1

3

High-throughput

0.445

High

717343

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.438

High

105415

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

353017

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

717308

UBE3C
Ubiquitin-protein ligase E3C

1

1

Small-scale

0.437

High

717315

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

717274

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.426

High

717266

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

337685

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.298

High

664944

ERD21
ER lumen protein-retaining receptor 1

2

0

High-throughput

0.298

High

717248

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

0

High-throughput

0.298

High

717273

TMM33
Transmembrane protein 33

2

0

High-throughput

0.298

High

717283

TYB10
Thymosin beta-10

2

0

High-throughput

0.298

High

717317

TMED4
Transmembrane emp24 domain-containing protein 4

2

0

High-throughput

0.298

High

717369

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.298

High

717323

GSDMB
Gasdermin-B

1

0

High-throughput

0.251

Low

283202

ERLN1
Erlin-1

1

0

Small-scale

0.249

Low

571379

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

717250

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

717287

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

717331

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.249

Low

717334

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

717348

LFG4
Protein lifeguard 4

1

0

High-throughput

0.249

Low

717355

TNR19
Tumor necrosis factor receptor superfamily member 19

1

0

Small-scale

0.249

Low

717364

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

717367

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

0

Small-scale

0.238

Low

717291

P
P protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025