HitPredict

Interactor 1: CADH3 (P22223)
Cadherin-3 (Placental cadherin) (P-cadherin)
Gene: CDH3

Interactor 2: CTNA1 (P35221)
Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)
Gene: CTNNA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	10910767, 10381631
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0007155 - cell adhesion GO:0016342 - catenin complex GO:0030054 - cell junction and 1 others more... GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 829 Hs			1 906
+	Mm
		454942 CADH1_MOUSE (1-829): 0: 690: 52.03		CTNA1_MOUSE (1-906): 0: 1074: 99.45
+	Hs
		606311 CADH3_HUMAN (1-829): 0: 754: 100.00		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		702744 CADH5_HUMAN (17-465): 1.64e-53: 201: 18.68		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Mm
		640688 CADH5_MOUSE (17-465): 4.7e-51: 194: 19.04		CTNA1_MOUSE (1-906): 0: 1074: 99.45
+	Hs
		716640 CADH8_HUMAN (9-318): 7.02e-47: 181: 16.95		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		716641 CAD12_HUMAN (7-318): 8.51e-43: 169: 14.89		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		640703 CADH5_HUMAN (17-465): 1.64e-53: 201: 18.68		CTNA2_HUMAN (6-905): 0: 1044: 77.87
+	Hs
		640713 CADH8_HUMAN (9-318): 7.02e-47: 181: 16.95		CTNA2_HUMAN (6-905): 0: 1044: 77.87
+	Hs
		640714 CAD12_HUMAN (7-318): 8.51e-43: 169: 14.89		CTNA2_HUMAN (6-905): 0: 1044: 77.87
+	Hs
		580206 CADH2_HUMAN (7-318): 5.56e-30: 129: 12.33		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		716725 CAD24_HUMAN (8-318): 1.75e-27: 121: 15.01		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		521757 CADH1_HUMAN (7-249): 7.79e-18: 90.7: 11.19		CTNA1_HUMAN (1-906): 0: 1080: 100.00
+	Hs
		1355726 CAD10_HUMAN (7-318): 4.59e-47: 182: 13.88		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		877559 CAD12_HUMAN (7-318): 8.51e-43: 169: 14.89		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		521735 CADH1_HUMAN (7-249): 7.79e-18: 90.7: 11.19		CTNA2_HUMAN (6-905): 0: 1044: 77.87
+	Hs
		877527 CADH4_HUMAN (9-324): 7.38e-34: 141: 14.60		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		580266 CADH2_HUMAN (7-318): 5.56e-30: 129: 12.33		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		1199809 CAD24_HUMAN (8-318): 1.75e-27: 121: 15.01		CTNA3_HUMAN (8-902): 0: 973: 59.22
+	Hs
		575694 CADH5_HUMAN (17-465): 1.64e-53: 201: 18.68		VINC_HUMAN (22-607): 1.07e-66: 244: 17.56
+	Hs
		521714 CADH1_HUMAN (7-249): 7.79e-18: 90.7: 11.19		VINC_HUMAN (22-607): 1.07e-66: 244: 17.56