Interactor 1: IL10 (P22301)
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)
Gene: IL10

Interactor 2: I10R2 (Q08334)
Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b)
Gene: IL10RB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 9312047, 20462497, 12513909
Identification Methods cross-linking study, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL10~Interfer-bind, IL10~Tissue_fac
Common GO terms GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 178
Hs

1 325
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024