Protein: CEBPE
CCAAT/enhancer-binding protein epsilon (C/EBP epsilon)

Gene: CEBPE
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q15744

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

886896

CEBPA
CCAAT/enhancer-binding protein alpha

3

19

Small-scale

0.840

High

921338

CEBPG
CCAAT/enhancer-binding protein gamma

2

18

Small-scale

0.793

High

775424

DDIT3
DNA damage-inducible transcript 3 protein

3

14

Small-scale

0.661

High

887424

CEBPD
CCAAT/enhancer-binding protein delta

1

20

Small-scale

0.653

High

370680

FOS
Protein c-Fos

1

20

High-throughput

0.647

High

429951

JUN
Transcription factor Jun

1

20

High-throughput

0.647

High

584025

FOSL1
Fos-related antigen 1

1

20

High-throughput

0.647

High

617167

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

20

High-throughput

0.647

High

617223

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

15

High-throughput

0.647

High

1152979

CEBPE
CCAAT/enhancer-binding protein epsilon

1

19

High-throughput

0.647

High

1152980

BATF
Basic leucine zipper transcriptional factor ATF-like

1

20

High-throughput

0.647

High

1152983

BATF2
Basic leucine zipper transcriptional factor ATF-like 2

1

20

High-throughput

0.647

High

1152994

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

1

20

High-throughput

0.647

High

1152998

ATF5
Cyclic AMP-dependent transcription factor ATF-5

1

20

High-throughput

0.647

High

1106336

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

13

High-throughput

0.618

High

297620

PIAS1
E3 SUMO-protein ligase PIAS1

1

4

Small-scale

0.586

High

391027

TRFL
Lactotransferrin

2

4

Small-scale

0.584

High

442725

RB
Retinoblastoma-associated protein

1

9

Small-scale

0.561

High

1029094

E2F1
Transcription factor E2F1

1

6

Small-scale

0.561

High

208669

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

3

Small-scale

0.552

High

343756

LDOC1
Protein LDOC1

1

2

Small-scale

0.552

High

993588

UBC9
SUMO-conjugating enzyme UBC9

1

4

Small-scale

0.552

High

1152995

ZMYM2
Zinc finger MYM-type protein 2

1

6

Small-scale

0.552

High

284951

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

8

High-throughput

0.541

High

576233

PO2F1
POU domain, class 2, transcription factor 1

1

13

High-throughput

0.541

High

1147165

ELOB
Elongin-B

1

1

High-throughput

0.541

High

1152981

ZFP2
Zinc finger protein ZFP2

1

4

High-throughput

0.541

High

1152982

MYCPP
C-myc promoter-binding protein

1

1

High-throughput

0.541

High

1152984

KC1AL
Casein kinase I isoform alpha-like

1

6

High-throughput

0.541

High

1152985

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.541

High

1152986

ZN384
Zinc finger protein 384

1

13

High-throughput

0.541

High

1152987

NELFB
Negative elongation factor B

1

1

High-throughput

0.541

High

1152990

GPR22
G-protein coupled receptor 22

1

1

High-throughput

0.541

High

1152992

ALX4
Homeobox protein aristaless-like 4

1

9

High-throughput

0.541

High

1152999

MED16
Mediator of RNA polymerase II transcription subunit 16

1

1

High-throughput

0.541

High

936553

AF17
Protein AF-17

1

7

Small-scale

0.527

High

1098300

TBX2
T-box transcription factor TBX2

1

0

High-throughput

0.518

High

1152993

TNR27
Tumor necrosis factor receptor superfamily member 27

1

0

High-throughput

0.518

High

590433

GATA1
Erythroid transcription factor

1

4

Small-scale

0.515

High

519379

MYB
Transcriptional activator Myb

1

8

Small-scale

0.501

High

1152991

TCPH
T-complex protein 1 subunit eta

1

14

High-throughput

0.494

High

1152996

TF2AY
TFIIA-alpha and beta-like factor

1

2

High-throughput

0.494

High

1153000

SERC
Phosphoserine aminotransferase

1

1

High-throughput

0.494

High

838237

STAT6
Signal transducer and activator of transcription 6

1

9

Small-scale

0.481

High

1152997

CSN3
COP9 signalosome complex subunit 3

1

6

Small-scale

0.481

High

461512

HS90A
Heat shock protein HSP 90-alpha

1

7

High-throughput

0.479

High

468407

HS90B
Heat shock protein HSP 90-beta

1

7

High-throughput

0.479

High

469425

ELNE
Neutrophil elastase

1

8

Small-scale

0.479

High

609932

SPI1
Transcription factor PU.1

1

16

Small-scale

0.479

High

748682

IL3RB
Cytokine receptor common subunit beta

1

8

Small-scale

0.479

High

1050738

MAD1
Max dimerization protein 1

1

19

Small-scale

0.479

High

1091108

FOXC1
Forkhead box protein C1

1

8

High-throughput

0.479

High

1122797

DOCK1
Dedicator of cytokinesis protein 1

1

3

Small-scale

0.479

High

1152989

CSF3R
Granulocyte colony-stimulating factor receptor

1

5

Small-scale

0.479

High

561007

IL7
Interleukin-7

1

2

High-throughput

0.439

High

567868

PRG2
Bone marrow proteoglycan

1

3

Small-scale

0.437

High

630130

AL5AP
Arachidonate 5-lipoxygenase-activating protein

1

2

Small-scale

0.437

High

69664

A8K673
Interleukin-7

1

2

High-throughput

0.417

High

1152988

TRIB1
Tribbles homolog 1

1

14

Small-scale

0.408

High


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Last updated: 11Aug2025