Interactor 1: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17785432
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death
Common GO terms GO:0006915 - apoptotic process
GO:0032757 - positive regulation of interleukin-8 production
GO:0032760 - positive regulation of tumor necrosis factor production
GO:0032991 - protein-containing complex
GO:0035591 - signaling adaptor activity
and 5 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 296
Mm

1 205
+ Hs
+ Xl
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024