Interactor 1: NDKB (P22392)
Nucleoside diphosphate kinase B (NDK B) (NDP kinase B) (EC 2.7.4.6) (C-myc purine-binding transcription factor PUF) (Histidine protein kinase NDKB) (EC 2.7.13.3) (nm23-H2)
Gene: NME2

Interactor 2: NDK3 (Q13232)
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)
Gene: NME3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 28514442, 16169070, 33961781, 11042679, 37071682
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NDK~NDK
Common GO terms GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006183 - GTP biosynthetic process
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 152
Hs

1 169
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024