Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: SRBP1 (P36956)
Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1 (Transcription factor SREBF1)]
Gene: SREBF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 19303849
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 310
Hs

1 1147
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024