HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: CDN2C (P42773)
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)
Gene: CDKN2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~I-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 168
+	Hs
		608184 FGFR4_HUMAN (13-802): 0: 750: 100.00		KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42
+	Hs
		601612 FGFR2_HUMAN (4-797): 0: 737: 56.44		KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42
+	Hs
		508236 FGFR1_HUMAN (3-794): 0: 706: 54.76		RAI14_HUMAN (1-135): 3.41e-37: 136: 21.32
+	Hs
		607908 FGFR4_HUMAN (13-802): 0: 750: 100.00		CDN2A_HUMAN (3-140): 5.49e-22: 88.2: 39.57
+	Hs
		607909 FGFR4_HUMAN (13-802): 0: 750: 100.00		CDN2B_HUMAN (9-122): 1.23e-20: 84: 45.22
+	Hs
		608115 FGFR4_HUMAN (13-802): 0: 750: 100.00		TANC1_HUMAN (82-168): 2.68e-12: 65.7: 22.47
+	Hs
		507971 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK3_HUMAN (77-168): 3.08e-25: 103: 41.30
+	Hs
		507954 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK2_HUMAN (77-168): 1.26e-23: 98.4: 40.22
+	Hs
		507831 FGFR1_HUMAN (3-794): 0: 706: 54.76		ANK1_HUMAN (72-168): 2.52e-19: 85.7: 35.05
+	Hs
		508185 FGFR1_HUMAN (3-794): 0: 706: 54.76		TANC1_HUMAN (82-168): 2.68e-12: 65.7: 22.47
+	Hs
		609438 FGFR3_HUMAN (5-799): 0: 712: 61.07		FANK1_HUMAN (2-59): 6.06e-10: 58.4: 18.97
+	Hs
		665439 EPHA3_HUMAN (4-778): 0: 595: 18.34		KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42
+	Hs
		665165 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2C_HUMAN (1-168): 3.27e-53: 168: 100.00
+	Hs
		872504 EPHA5_HUMAN (4-771): 0: 580: 18.81		KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42
+	Hs
		665360 EPHA2_HUMAN (4-789): 0: 573: 19.58		KDIS_HUMAN (2-159): 8.8e-46: 161: 26.42
+	Hs
		665376 EPHA3_HUMAN (4-778): 0: 595: 18.34		CDN2A_HUMAN (3-140): 5.49e-22: 88.2: 39.57
+	Hs
		665163 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2A_HUMAN (3-140): 5.49e-22: 88.2: 39.57
+	Hs
		665164 EPHA2_HUMAN (4-789): 0: 573: 19.58		CDN2B_HUMAN (9-122): 1.23e-20: 84: 45.22
+	Hs
		665581 EPHB2_HUMAN (4-779): 0: 557: 17.27		ANK2_HUMAN (77-168): 1.26e-23: 98.4: 40.22
+	Hs
		665280 EPHA2_HUMAN (4-789): 0: 573: 19.58		MIB1_HUMAN (74-168): 4.43e-14: 70.7: 21.88