HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 870
+	Hs
		601480 FGFR2_HUMAN (4-797): 0: 737: 56.44		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609215 FGFR3_HUMAN (5-799): 0: 712: 61.07		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		507913 FGFR1_HUMAN (3-794): 0: 706: 54.76		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		608198 FGFR4_HUMAN (13-802): 0: 750: 100.00		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		601616 FGFR2_HUMAN (4-797): 0: 737: 56.44		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		609615 FGFR3_HUMAN (5-799): 0: 712: 61.07		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		508270 FGFR1_HUMAN (3-794): 0: 706: 54.76		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		384503 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		384691 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		128396 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		DNM1L_HUMAN (6-743): 0: 787: 39.13
+	Hs
		729628 VGFR2_HUMAN (74-376): 3.42e-24: 111: 16.67		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		572603 VGFR1_HUMAN (26-128): 1.78e-10: 67: 22.22		DYN2_HUMAN (1-870): 0: 1057: 100.00