HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 1118
+	Hs
		601509 FGFR2_HUMAN (4-797): 0: 737: 56.44		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		507992 FGFR1_HUMAN (3-794): 0: 706: 54.76		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		665396 EPHA3_HUMAN (4-778): 0: 595: 18.34		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		1048589 EPHA7_HUMAN (4-781): 0: 584: 19.90		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		872645 EPHA4_HUMAN (4-776): 0: 582: 19.47		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		872440 EPHA5_HUMAN (4-771): 0: 580: 18.81		DSG2_HUMAN (1-1118): 0: 1174: 100.00
+	Hs
		507929 FGFR1_HUMAN (3-794): 0: 706: 54.76		CAD11_HUMAN (9-848): 0: 645: 22.22
+	Hs
		507817 FGFR1_HUMAN (3-794): 0: 706: 54.76		CADH1_HUMAN (22-670): 0: 577: 31.67
+	Hs
		521744 EPHA2_HUMAN (4-789): 0: 573: 19.58		CADH1_HUMAN (22-670): 0: 577: 31.67
+	Hs
		508294 FGFR1_HUMAN (3-794): 0: 706: 54.76		PCDB7_HUMAN (54-599): 4.83e-92: 314: 19.42
+	Xl
		292719 FGFR1_XENLA (1-799): 0: 696: 54.37		O93264_XENLA (1-493): 2.12e-78: 276: 18.63
+	Hs
		507842 FGFR1_HUMAN (3-794): 0: 706: 54.76		CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52
+	Hs
		508000 FGFR1_HUMAN (3-794): 0: 706: 54.76		DSC3_HUMAN (28-361): 8.23e-29: 126: 16.86
+	Hs
		580236 EPHA7_HUMAN (4-781): 0: 584: 19.90		CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52
+	Hs
		580213 EPHA4_HUMAN (4-776): 0: 582: 19.47		CADH2_HUMAN (1-489): 2.19e-63: 234: 18.52
+	Hs
		872598 EPHB4_HUMAN (4-781): 4.88e-171: 521: 17.66		PCDB3_HUMAN (57-599): 1.32e-84: 293: 18.34
+	Hs
		971014 EPHA7_HUMAN (4-781): 0: 584: 19.90		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		872632 EPHA4_HUMAN (4-776): 0: 582: 19.47		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		872427 EPHA5_HUMAN (4-771): 0: 580: 18.81		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90
+	Hs
		665215 EPHA2_HUMAN (4-789): 0: 573: 19.58		DSC2_HUMAN (28-494): 8.1e-51: 196: 16.90