Protein: BT2A2
Butyrophilin subfamily 2 member A2

Gene: BT2A2, BTN2A2
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q8WVV5

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0001817 - regulation of cytokine production
GO:0001818 - negative regulation of cytokine production
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

705980

CD1B
T-cell surface glycoprotein CD1b

3

9

High-throughput

0.861

High

1270275

BT2A1
Butyrophilin subfamily 2 member A1

3

16

High-throughput

0.861

High

1358628

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

3

2

High-throughput

0.861

High

1057568

ACHD
Acetylcholine receptor subunit delta

2

2

High-throughput

0.811

High

1358623

PCDBG
Protocadherin beta-16

2

6

High-throughput

0.811

High

1358630

PCDGG
Protocadherin gamma-B4

2

7

High-throughput

0.811

High

1358637

PCDG5
Protocadherin gamma-A5

2

7

High-throughput

0.811

High

1358638

PCDC2
Protocadherin alpha-C2

2

7

High-throughput

0.811

High

194727

FFAR2
Free fatty acid receptor 2

2

1

High-throughput

0.783

High

590322

MUC1
Mucin-1

2

2

High-throughput

0.783

High

622087

CD53
Leukocyte surface antigen CD53

2

3

High-throughput

0.783

High

639152

SYT1
Synaptotagmin-1

2

2

High-throughput

0.783

High

844843

EAA1
Excitatory amino acid transporter 1

2

2

High-throughput

0.783

High

850845

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.783

High

1186006

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.783

High

1358626

GPC5D
G-protein coupled receptor family C group 5 member D

2

3

High-throughput

0.783

High

1358614

GPR21
Probable G-protein coupled receptor 21

2

0

High-throughput

0.770

High

1358624

I17RB
Interleukin-17 receptor B

2

0

High-throughput

0.770

High

549839

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.742

High

932699

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.742

High

1010505

EREP3
Protein ENTREP3

2

1

High-throughput

0.705

High

1108988

AQP6
Aquaporin-6

2

2

High-throughput

0.700

High

1251707

SPNS3
Protein spinster homolog 3

2

2

High-throughput

0.700

High

1358633

TMX2
Thioredoxin-related transmembrane protein 2

2

2

High-throughput

0.700

High

127710

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

3

High-throughput

0.691

High

607964

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

2

High-throughput

0.691

High

688602

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

1

High-throughput

0.691

High

1180941

HFE
Hereditary hemochromatosis protein

1

7

High-throughput

0.691

High

1295787

C1QL4
Complement C1q-like protein 4

1

3

High-throughput

0.691

High

1352081

TS1R2
Taste receptor type 1 member 2

1

2

High-throughput

0.691

High

1358618

RXFP1
Relaxin receptor 1

1

4

High-throughput

0.691

High

1358634

PCDB6
Protocadherin beta-6

1

6

High-throughput

0.691

High

1358635

PCDGM
Protocadherin gamma-C5

1

6

High-throughput

0.691

High

1358636

PCDGE
Protocadherin gamma-B2

1

7

High-throughput

0.691

High

1198730

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.679

High

931420

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

1

High-throughput

0.667

High

1358629

AT1B4
Protein ATP1B4

3

1

High-throughput

0.667

High

1358632

ITM2B
Integral membrane protein 2B

3

1

High-throughput

0.667

High

193432

GPR42
G-protein coupled receptor 42

1

1

High-throughput

0.665

High

821683

TPOR
Thrombopoietin receptor

1

0

High-throughput

0.656

High

142103

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.655

High

1358615

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.655

High

779722

MOT8
Monocarboxylate transporter 8

1

2

High-throughput

0.621

High

1134135

NTCP
Hepatic sodium/bile acid cotransporter

1

1

High-throughput

0.621

High

166366

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

2

3

High-throughput

0.606

High

1159612

STX1A
Syntaxin-1A

2

1

High-throughput

0.606

High

1358620

S39A2
Zinc transporter ZIP2

2

4

High-throughput

0.606

High

1244889

NCEH1
Neutral cholesterol ester hydrolase 1

2

0

High-throughput

0.602

High

761159

EVI2B
Protein EVI2B

2

0

High-throughput

0.580

High

1102801

UT1
Urea transporter 1

2

0

High-throughput

0.580

High

1281747

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

1347182

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.580

High

1358613

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1248537

LCTL
Lactase-like protein

1

0

High-throughput

0.578

High

380567

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

10

High-throughput

0.575

High

1358610

TMED6
Transmembrane emp24 domain-containing protein 6

2

2

High-throughput

0.574

High

1358611

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

6

High-throughput

0.574

High

291731

CXB3
Gap junction beta-3 protein

2

3

High-throughput

0.553

High

1352469

GPX8
Probable glutathione peroxidase 8

2

3

High-throughput

0.553

High

1358625

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

137360

NPT4
Sodium-dependent phosphate transport protein 4

1

0

High-throughput

0.546

High

1185820

PTHD3
Patched domain-containing protein 3

1

7

High-throughput

0.536

High

1358639

PTC2
Protein patched homolog 2

1

7

High-throughput

0.536

High

681461

PSA3
Proteasome subunit alpha type-3

1

2

High-throughput

0.523

High

926812

VMAT1
Chromaffin granule amine transporter

1

0

High-throughput

0.519

High

248495

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.513

High

1195452

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1203749

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1211816

DCST1
E3 ubiquitin-protein ligase DCST1

1

0

High-throughput

0.513

High

1333582

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1358621

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.513

High

771844

UD15
UDP-glucuronosyltransferase 1A5

1

2

High-throughput

0.489

High

1085354

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

12

High-throughput

0.489

High

230373

CREB3
Cyclic AMP-responsive element-binding protein 3

1

7

High-throughput

0.464

High

386025

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

17

High-throughput

0.439

High

1187510

AR13B
ADP-ribosylation factor-like protein 13B

1

6

High-throughput

0.439

High

1084056

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

2

0

High-throughput

0.318

High

1102422

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

1142899

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

1195248

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

1207566

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1327904

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.316

High

1358616

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

1358617

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

1358619

MRM3
rRNA methyltransferase 3, mitochondrial

2

0

High-throughput

0.316

High

1358631

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

1358612

FATE1
Fetal and adult testis-expressed transcript protein

1

0

High-throughput

0.299

High

1358627

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1207738

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

1358622

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025