HitPredict

Interactor 1: RARB (P22605)
Retinoic acid receptor beta (RAR-beta) (Nuclear receptor subfamily 1 group B member 2)
Gene: RARB

Interactor 2: RORG (P51450)
Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Nuclear receptor subfamily 1 group F member 3) (RAR-related orphan receptor C) (Retinoid-related orphan receptor-gamma) (Thymus orphan receptor) (TOR)
Gene: Rorc

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24670648
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0004879 - nuclear receptor activity GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding and 1 others more... GO:0030154 - cell differentiation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 482 Mm			1 516
+	Hs
		265857 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		NR1I2_HUMAN (8-507): 5.8e-78: 253: 21.81
+	Mm
		579888 RARB_MOUSE (1-482): 3.89e-163: 471: 100.00		RARG_MOUSE (4-145): 1.19e-45: 168: 40.56
+	Hs
		500357 RARB_HUMAN (1-482): 5.45e-156: 452: 92.32		RXRG_HUMAN (19-216): 1.06e-48: 176: 28.79
+	Hs
		500354 RARB_HUMAN (1-482): 5.45e-156: 452: 92.32		RXRA_HUMAN (3-203): 1.29e-48: 175: 27.10
+	Mm
		222607 RXRG_MOUSE (2-444): 2.76e-132: 392: 29.37		NR1I2_MOUSE (29-507): 8.75e-70: 231: 21.03
+	Hs
		509920 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		VDR_HUMAN (14-508): 6.1e-70: 231: 17.69
+	Hs
		487885 RARB_HUMAN (1-482): 5.45e-156: 452: 92.32		RARA_HUMAN (3-145): 1.78e-44: 164: 38.19
+	Mm
		509288 RARA_MOUSE (1-454): 2.62e-132: 392: 76.70		RXRA_MOUSE (19-203): 7.23e-49: 176: 30.11
+	Hs
		587136 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		RXRA_HUMAN (3-203): 1.29e-48: 175: 27.10
+	Hs
		740462 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		PPARG_HUMAN (3-155): 1.44e-46: 171: 35.07
+	Hs
		500356 RARB_HUMAN (1-482): 5.45e-156: 452: 92.32		RXRB_HUMAN (31-111): 2.94e-24: 108: 55.56
+	Hs
		530789 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		RARG_HUMAN (4-145): 5.29e-46: 168: 40.56
+	Hs
		487920 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		RARA_HUMAN (3-145): 1.78e-44: 164: 38.19
+	Mm
		659751 RXRG_MOUSE (2-444): 2.76e-132: 392: 29.37		PPARD_MOUSE (29-119): 1.29e-41: 156: 52.17
+	Hs
		818868 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		PPARD_HUMAN (29-132): 4.63e-42: 157: 49.52
+	Mm
		659756 RXRG_MOUSE (2-444): 2.76e-132: 392: 29.37		NR1H3_MOUSE (7-329): 3.43e-38: 147: 17.90
+	Hs
		500468 RXRG_HUMAN (2-444): 9.83e-132: 391: 28.92		THB_HUMAN (31-139): 8.47e-37: 143: 40.54
+	Mm
		659752 RXRG_MOUSE (2-444): 2.76e-132: 392: 29.37		THB_MOUSE (31-139): 2.78e-36: 142: 39.64
+	Mm
		659754 RXRG_MOUSE (2-444): 2.76e-132: 392: 29.37		NR1H2_MOUSE (14-159): 5.72e-34: 135: 30.41