HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 806 Hs			1 540
+	Hs
		609282 FGFR3_HUMAN (10-806): 0: 819: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		609552 FGFR3_HUMAN (10-806): 0: 819: 100.00		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		280018 FGFR3_HUMAN (10-806): 0: 819: 100.00		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		665433 EPHA3_HUMAN (1-786): 0: 641: 20.68		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1072604 EPHA7_HUMAN (1-782): 0: 626: 21.22		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		665663 EPHB2_HUMAN (1-788): 0: 624: 19.15		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1072612 EPHA7_HUMAN (1-782): 0: 626: 21.22		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		872493 EPHA5_HUMAN (1-777): 0: 622: 20.18		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		872713 EPHA4_HUMAN (1-781): 0: 622: 20.78		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		665667 EPHB2_HUMAN (1-788): 0: 624: 19.15		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		872496 EPHA5_HUMAN (1-777): 0: 622: 20.18		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		872718 EPHA4_HUMAN (1-781): 0: 622: 20.78		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		1021499 EPHA7_HUMAN (1-782): 0: 626: 21.22		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		872433 EPHA5_HUMAN (1-777): 0: 622: 20.18		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		872639 EPHA4_HUMAN (1-781): 0: 622: 20.78		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		1081612 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		1081620 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		LIN7C_HUMAN (85-202): 2.22e-35: 133: 34.75
+	Hs
		1021503 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51
+	Hs
		942352 NTRK2_HUMAN (159-756): 1.53e-161: 491: 25.51		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		280015 KIT_HUMAN (19-794): 1.17e-165: 506: 24.62		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07