Protein: COS6
Protein COS6

Gene: COS6
Organism: Saccharomyces cerevisiae S288C
Interactions: 23
UniProt ID: P53344

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0005768 - endosome
GO:0016020 - membrane
GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

815519

RSP5
E3 ubiquitin-protein ligase RSP5

2

2

Small-scale

0.595

High

818126

SHO1
High osmolarity signaling protein SHO1

1

2

High-throughput

0.541

High

917989

MST27
Multicopy suppressor of SEC21 protein 27

1

13

High-throughput

0.541

High

919816

FMP42
Protein FMP42

1

2

High-throughput

0.541

High

919818

GAS2
1,3-beta-glucanosyltransferase GAS2

1

1

High-throughput

0.541

High

919819

ATX2
Metal homeostasis factor ATX2

1

1

High-throughput

0.541

High

919821

VCX1
Vacuolar calcium ion transporter

1

0

High-throughput

0.518

High

528617

CP51
Lanosterol 14-alpha demethylase CYP51

1

2

High-throughput

0.494

High

609282

CPT1
Cholinephosphotransferase 1

1

2

High-throughput

0.494

High

672827

ELO2
Fatty acid elongase 2

1

10

High-throughput

0.494

High

781306

AUR1
Inositol phosphorylceramide synthase catalytic subunit AUR1

1

2

High-throughput

0.494

High

797428

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

7

High-throughput

0.494

High

822326

ELO3
Fatty acid elongase 3

1

10

High-throughput

0.494

High

919814

SHR3
Secretory component protein SHR3

1

3

High-throughput

0.494

High

919815

GSF2
Glucose-signaling factor 2

1

3

High-throughput

0.494

High

919817

THI7
Thiamine transporter

1

4

High-throughput

0.494

High

919812

COS1
Protein COS1

1

13

High-throughput

0.479

High

506207

AQY1
Aquaporin-1

1

2

High-throughput

0.439

High

705208

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

393101

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.417

High

919813

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.417

High

919820

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

830013

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025